The National Institutes of Health is offering a grant opportunity titled "Adolescent Overdose Prevention and SUD Treatment Initiative (R21 - Clinical Trial Not Allowed)". This grant aims to support exploratory and developmental research to better understand adolescent illicit fentanyl use and overdose patterns among youth at high risk for overdose. The research studies funded by this grant should identify targets for overdose prevention and substance use disorder (SUD) treatment and recovery. Various research approaches can be used, such as leveraging existing data sources, survey research, social network analysis, new methods development, and feasibility research. The outcomes of interest include the prevalence of overdose and reduction in substance use, particularly fentanyl use or use of drugs commonly laced with fentanyl, unintentional use/overdose, use/overdose by risk group, stigma, family and environmental risk and protective factors, treatment engagement, youth perceptions of substance use, and optimistic bias. The grant does not require cost sharing or matching. The deadline for application submission is March 13, 2024. For more information and to apply, visit the following link: Adolescent Overdose Prevention and SUD Treatment Initiative Grant.