The U.S. National Science Foundation (NSF) is offering the EPSCoR Research Infrastructure Improvement Program, specifically targeting collaborations to optimize research ecosystems within eligible jurisdictions. This grant aims to enhance research infrastructure and development capacity by fostering partnerships among academic institutions, government, industry, and non-profit sectors, focusing on sustainable improvements in research capabilities. The program supports a variety of initiatives, including the development of research administration, facilities, STEM education pathways, and workforce development, with a total estimated funding of $37.5 million and a minimum award amount of $16 million. Interested applicants, including institutions of higher education and non-profit organizations, should refer to the NSF publication for further details and can contact NSF grants.gov support at grantsgovsupport@nsf.gov for assistance.