The National Science Foundation (NSF) is offering the EPSCoR Collaborations for Optimizing Research Ecosystems Research Infrastructure Improvement Program, a federal grant aimed at enhancing research infrastructure in EPSCoR-eligible jurisdictions. This program seeks to establish partnerships among academic institutions, government, industry, and non-profit sectors to promote sustainable improvements in research capacity and competitiveness. The initiative is crucial for developing jurisdiction-wide research administration, facilities, and STEM education pathways, ultimately fostering a robust research ecosystem. The estimated total program funding is $37.5 million, with a minimum award amount of $16 million, and proposals are due by July 8, 2025. For further inquiries, interested applicants can contact NSF grants.gov support at grantsgovsupport@nsf.gov.