The Administration for Community Living is forecasting a funding opportunity titled "Projects of National Significance," aimed at supporting initiatives that enhance the lives of individuals with developmental disabilities. This cooperative agreement will focus on creating opportunities for these individuals to participate fully in community life and to influence national and state policies that promote their self-determination and inclusion. With an estimated total program funding of $3,750,000, the agency anticipates awarding approximately 10 grants, each ranging from $350,000 to $400,000. Interested applicants, particularly nonprofits without 501(c)(3) status, can find more information and contact Thom Campbell at thom.campbell@acl.hhs.gov, with proposals expected to be submitted by July 15, 2022, and project start dates anticipated for September 1, 2022.