The National Institutes of Health (NIH) is preparing to publish a Notice of Funding Opportunity (NOFO) for the Metastasis Research Network (MetNet), specifically targeting research projects under the U01 Clinical Trial Not Allowed funding mechanism. This initiative aims to solicit applications that utilize integrative systems-level approaches to address critical questions in metastasis research, aligning with the ongoing efforts of the MetNet, which focuses on understanding the complex dynamics of metastasis through collaborative research. The anticipated NOFO is expected to be published in Summer 2025, with applications due in Fall 2025, and will support approximately 10 awards, with no cost-sharing or matching requirements. For further inquiries, interested applicants can contact Joanna M. Watson, Ph.D., at watsonjo@mail.nih.gov or by phone at 240-276-6206.