The National Institutes of Health (NIH) is preparing to publish a Notice of Funding Opportunity (NOFO) for the EmbraceHealth Clinical Research Network, aimed at reducing health disparities through a Coordinating Center. This initiative seeks to establish a robust infrastructure for conducting research that addresses urgent health needs among populations facing health disparities, with a focus on developing and implementing clinical and behavioral interventions. The Coordinating Center will play a crucial role in coordinating research activities, providing biostatistical support, and ensuring data management across multiple sites. Interested applicants, particularly small businesses, can reach out to Dr. Larissa Avilés-Santa at avilessantal@nih.gov or call 301-827-6924 for further information. The estimated synopsis post date is November 28, 2025, with applications expected to close by February 2, 2026, and project start dates anticipated for September 1, 2026.

The National Institute on Minority Health and Health Disparities (NIMHD) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for the Coordinating Center for the EmbraceHealth Clinical Research Network. The overarching goals of the EmbraceHealth Network are to establish and maintain an efficient and nimble infrastructure to conduct research to address emerging, urgent, or chronic health needs among populations that experience health disparities. Each site within the Network will conduct research to develop, test, and implement clinical and behavioral interventions and services that address key public health needs and diseases with evidence of health disparities. Interventions will be designed and evaluated using robust scientific methods and must demonstrate feasibility, scalability, and reproducibility. The EmbraceHealth Network will serve the purpose of improving routine healthcare services as well as linking clinical practice and science within lower resourced healthcare settings.The Coordinating Center will support the Clinical Research Network sites by:Coordinating research activities, including the Steering Committee and workgroups.Identifying network personnel and clinicians for study teams.Developing operational manuals and standardized protocols for multi-site studies, including consent and IRB processes.Assisting CRN sites in implementing projects with technical and quality control support.Maintaining a data management system for study data, including guidance from NIMHD.Standardizing protocols for common data elements, including biospecimen and electronic health record (EHR) data collection.Providing biostatistical support for study design, implementation, and analyses.Advising on infrastructure development, including electronic data harmonization and data science expertise.Coordinating data-sharing plans among CRN sites.Ensuring secure storage and access to study-related materials.Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. In addition, collaborative investigations combining expertise in multiple scientific and clinical disciplines will be encouraged.Activity Code:This NOFO will utilize the U24 (Research Program Grant Cooperative Agreements) activity code. 

Forecast to Publish a Funding Opportunity Announcement for EmbraceHealth Clinical Research Network to Reduce Health Disparities &#8211; Coordinating Center

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