The National Institutes of Health (NIH) is offering a limited competition grant for the continuation of the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) Data Analysis Resource, with a focus on understanding the impact of adolescent alcohol use on brain development and behavior. This cooperative agreement aims to support research that follows participants up to 37 years of age, providing critical data to inform evidence-based alcohol prevention strategies and interventions. The estimated total program funding is $600,000, with one award expected to be made, and interested applicants are encouraged to prepare collaborations in advance, as applications are not currently being solicited. For further inquiries, potential applicants can contact Dominique Lorang-Leins at 301-594-6228 or via email at lorangd@mail.nih.gov, with key deadlines including an estimated synopsis post date of September 1, 2025, and an estimated award date of July 1, 2027.

The National Institute on Alcohol Abuse and Alcoholism (NIAAA) launched the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) in 2012 to determine how adolescent alcohol-related disruption of normal brain growth patterns of structure, related brain function, and psychiatric health affects brain functioning in emerging adulthood. The consortium uses an accelerated longitudinal design and has acquired data on over 800 individuals between the ages of 12 to 32 years. This wide age range covers the period before onset of drinking, the transition from adolescence to young adulthood, the critical period for binge drinking, and the time of maturing out. This unique dataset provides novel information on the enduring and transient consequences of adolescent drinking on adult brain function and behavior. Current studies on adults drinking do not have this type of data. Renewal of this limited competition NOFO will enable NCANDA to continue to follow these participants up to 37 years of age and acquire data critical to understanding how early versus late onset drinking during adolescence differentially impacts drinking behavior in adulthood. This limited competition renewal will provide valuable information for developing evidence-based alcohol prevention strategies and early intervention approaches to prevent the progression to more severe drinking and AUD thereby preventing the development of chronic disease, improving health outcomes, and increasing quality of life and longevity. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the U24 activity code. Investigators with expertise and insights into this area of integrative neuroscience are encouraged to begin to consider applying for this new NOFO. 

Limited Competition for the Continuation of the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) Data Analysis Resource (U24 Clinical Trials Optional)

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