The Centers for Disease Control and Prevention - ERA is offering a grant opportunity titled "Demonstration Projects to Research and Evaluate Strategies Aligned with CDC's What Works in Schools Approach". This grant aims to support research and evaluation of strategies aligned with CDC's What Works in Schools (WWIS) approach for successful implementation in local education agencies and schools serving rural or American Indian and/or Alaska Native (AI/AN) adolescents. The research will focus on addressing students' health behaviors, experiences, and outcomes, particularly related to sexual and reproductive health, mental and behavioral health, suicidality, substance use, and experiences of violence. The grant seeks to build the evidence base for innovative, school-based or school-linked strategies that promote the health of youth across multiple health domains while also supporting translation and dissemination of the research findings. The grant has an estimated total program funding of $5,000,000 and expects to make 2 awards. The application deadline is April 1, 2024, at 11:59 pm ET. For more information, contact Dr. Celeste Sanders at CSanders4@cdc.gov.