The National Institutes of Health (NIH) is set to publish a Funding Opportunity Announcement for Cancer Center Support Grants (CCSGs) aimed at NCI-designated Cancer Centers. This initiative invites applications from small businesses to support various types of Cancer Centers, including Comprehensive, Clinical, and Basic Cancer Centers, with the goal of enhancing cancer research capabilities and fostering collaboration across institutional boundaries. The CCSGs are crucial for advancing the understanding of cancer and developing effective prevention, diagnosis, and treatment strategies. Interested applicants can reach out to the Office of Cancer Centers at the National Cancer Institute via email at ncicenters-r@mail.nih.gov or by phone at 240-276-5600. The estimated synopsis will be posted on October 1, 2025, with applications closing on January 25, 2026, and awards expected to be made by December 1, 2026.