Chemical Countermeasures Research Program (CCRP) Initiative: Basic Research on The Deleterious Effects of Acute Exposure to Ultra-Potent Synthetic (UPS) Opioids (R01 Clinical Trial Not Allowed)
ID: 357250Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Award Range

$0 - $300K

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes
Timeline
    Description

    The National Institutes of Health (NIH) is offering a funding opportunity through the Chemical Countermeasures Research Program (CCRP) Initiative, aimed at supporting research on the harmful effects of acute exposure to Ultra-Potent Synthetic (UPS) opioids, such as fentanyl and carfentanil. This initiative seeks to advance understanding of both immediate and delayed health impacts associated with these substances, emphasizing innovative research into toxicity mechanisms and the development of new therapeutic strategies. The program will provide up to four grants, with a maximum award of $300,000 annually over a potential five-year period, totaling an estimated $2 million in funding. Interested applicants, including various educational and nonprofit institutions, must submit their proposals by November 18, 2027, and can direct inquiries to grantsinfo@nih.gov for further information.

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    Title
    Posted
    The Department of Health and Human Services, through the National Institutes of Health (NIH), announces the Chemical Countermeasures Research Program (CCRP) Initiative which aims to support research into the harmful effects of acute exposure to Ultra-Potent Synthetic (UPS) opioids like fentanyl and carfentanil. The funding opportunity (RFA-DA-26-034) emphasizes understanding the immediate and delayed health impacts of these chemicals, which have been classified as high-consequence due to their danger in both public health and potential military applications. The initiative seeks innovative research focusing on mechanisms of toxicity, historical knowledge gaps regarding molecular effects, and the development of new therapeutic strategies. Grants will provide up to four awards totaling $2 million for projects not exceeding $300,000 annually over a potential five-year period. Eligibility includes a wide range of institutions, such as higher education and nonprofit organizations, but excludes foreign entities. Applications must avoid focusing solely on traditional opioid mechanisms and must propose pathways for innovative drug discovery aimed at UPS opioid exposure. The announcement includes specific application guidelines and deadlines, with an aim to advance the understanding and mitigation of opioid-related health crises.
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