The Centers for Disease Control and Prevention (CDC) has announced a Notice of Funding Opportunity (NOFO) titled "Health Promotion and Disease Prevention Research Centers: 2025 Special Interest Project Competitive Supplements" (RFA-DP-25-126) to provide supplemental funding for previously funded Health Promotion and Disease Prevention Research Centers (PRCs). This initiative aims to support high-quality applied research that informs public health practices and addresses major health challenges, including cancer, diabetes, and obesity, in alignment with the Healthy People 2030 objectives. The total estimated funding available is $21,858,000, with up to 12 awards anticipated, and applications must be submitted electronically through Grants.gov by February 28, 2025, with a Letter of Intent due by February 5, 2025. For further inquiries, applicants can contact Natalie J. Darling at ndh6@cdc.gov.