The National Institutes of Health (NIH) is inviting applications for Cancer Center Support Grants (CCSGs) aimed at supporting NCI-designated Cancer Centers, including Comprehensive, Clinical, and Basic Cancer Centers. Applicants must demonstrate a substantial base of NIH cancer-focused funding, with requirements of $10 million for Clinical and Comprehensive Centers, and $6 million for Basic Centers for new applicants, while renewal applicants must also meet a $10 million threshold. These grants are crucial for advancing interdisciplinary research to reduce cancer incidence, mortality, and morbidity, providing resources for scientific leadership, shared facilities, and administrative costs over a five-year term, with a possible two-year extension based on merit. Interested institutions can contact the Office of Cancer Centers at ncicenters-r@mail.nih.gov for further information, with applications due by September 25, 2028.

PAR-25-444-Full-Announcement.html

The Department of Health and Human Services, National Institutes of Health, and National Cancer Institute invite applications for Cancer Center Support Grants (CCSGs) for NCI-designated Cancer Centers (PAR-25-444). This funding opportunity, a reissue of PAR-21-321, aims to support Comprehensive, Clinical, and Basic Cancer Centers in their efforts to reduce cancer incidence, mortality, and morbidity through interdisciplinary research. The grant provides resources for scientific leadership, shared facilities, administrative costs, planning, and developmental funds. Eligibility requires a substantial base of NIH cancer-focused funding ($10M for Clinical/Comprehensive, $6M for Basic new applicants, $10M for all renewal applicants) and adherence to six essential characteristics, including physical space, organizational capabilities, transdisciplinary collaboration, cancer focus, institutional commitment, and strong Center Director leadership. The grant term is five years, with an optional two-year extension based on merit.

This Notice of Funding Opportunity (NOFO) invites applications for P30 Cancer Center Support Grants (CCSGs) to support NCI-Designated Cancer Centers. CCSGs support three types of Cancer Centers: 1) Comprehensive Cancer Centers, which demonstrate reasonable depth and breadth of research activities in each of three major areas: basic laboratory; clinical; and prevention, control and population-based research, and which have substantial transdisciplinary research that bridges these scientific areas; and 2) Clinical Cancer Centers, which are primarily focused on basic laboratory; clinical; and prevention, cancer control, and population-based research; or some combination of these areas, and 3) Basic Cancer Centers, which focus on basic laboratory research. The purpose of all types of NCI-Designated Cancer Centers is to capitalize on all institutional cancer research capabilities, integrating meritorious research into a single transdisciplinary research enterprise across all institutional boundaries. Cancer Centers supported through this NOFO are expected to serve as major sources of discovery of the nature of cancer and of development of more effective approaches to prevention, diagnosis, and therapy; to contribute significantly to the development of Shared Resources that support research; to collaborate and coordinate their research efforts with other NCI-funded programs and investigators; and to disseminate research findings for the benefit of the community.

Office of Cancer Centers&lt;br/&gt;National Cancer Institute (NCI)&lt;br/&gt;ncicenters-r@mail.nih.gov

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