The Fiscal Year 2025 Department of Defense Alzheimer’s Research Program (AZRP) outlines three distinct award mechanisms aimed at advancing research on Alzheimer’s disease and related conditions. Each mechanism has specific eligibility criteria, funding specifics, and submission deadlines.
1. **Transforming Diagnosis Award**: Targets research to enhance diagnosis and prognosis of Alzheimer’s in military populations, allowing for up to $1.5 million over four years, with a pre-application deadline of June 12, 2025, and a final application due August 29, 2025.
2. **Transforming Research Award**: Focuses on reducing the risk of Alzheimer’s with high-impact research outcomes, providing a maximum funding of $1 million over three years. Similar deadlines apply.
3. **Transforming Care Award**: Aims at person-centered care research, allowing clinical trials and offering up to $1.6 million over four years. It emphasizes feasibility and scalability of solutions. All mechanisms require preliminary data and community collaboration.
Pre-proposals are required for initial screening, and applications are by invitation only, reflecting a structured approach to funding research initiatives aligned with military and health objectives.
The Department of Defense (DoD) is announcing the FY25 Alzheimer’s Research Program's Transforming Research Award, aiming to fund innovative research aimed at reducing the risk of Alzheimer’s Disease and related dementias (AD/ADRD). With an anticipated budget of $4 million distributed across approximately four awards, each application may request up to $1 million over a maximum of three years. The award encourages diverse applicant organizations, including for-profit, non-profit, and academic institutions, and demands active community collaboration for clinical research projects.
The application process consists of a two-step submission: an initial pre-application and a subsequent full application. Key evaluation criteria include the significance and innovative potential of the proposed research, feasibility, and adherence to guidelines focused on addressing critical issues in AD/ADRD. The program requires applications to demonstrate community-informed research approaches and robust methodologies, discouraging merely incremental advancements.
Importantly, applicants must provide means for actively engaging the community in research processes and outcomes. The full proposal submission will follow a detailed format, including a project narrative, budget justification, and supporting documentation, with deadlines for pre-applications set for June 12, 2025, and full applications due August 29, 2025. The announcement emphasizes the need for transparency, rigor, and collaboration to tackle pressing health challenges impacting military personnel, veterans, and the general public affected by dementia.