DOD Peer Reviewed Cancer, Clinical Trial Award
ID: 359096Type: Posted
Overview

Buyer

Dept. of the Army -- USAMRAA (DOD-AMRAA)

Eligible Applicants

Unrestricted

Funding Category

Science and Technology and other Research and Development

Funding Instrument

Grant

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes
Timeline
    Description

    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering a grant opportunity for the fiscal year 2025 under the Peer Reviewed Cancer Research Program (PRCRP) Clinical Trial Award (CTA). This grant aims to support the rapid implementation of clinical trials that have the potential to significantly impact cancer treatment, specifically targeting designated cancer types relevant to military health. The program emphasizes the importance of advancing cancer research to benefit service members, veterans, and their families, with funding available for projects ranging from initial proof-of-concept trials to large-scale phase III trials, capped at a total cost of $4.2 million over a maximum performance period of four years. Interested applicants must submit pre-applications by June 20, 2025, followed by full applications due by September 25, 2025, and can reach out to the CDMRP Help Desk at help@eBRAP.org for further assistance.

    Point(s) of Contact
    Files
    Title
    Posted
    The Department of Defense's Peer Reviewed Cancer Research Program (PRCRP) Clinical Trial Award (CTA) for fiscal year 2025 aims to support clinical trials that demonstrate significant potential in cancer treatment, specifically addressing designated topic areas relevant to military health. Applications are accepted from both domestic and international organizations, provided that principal investigators hold appropriate qualifications. Key details include: - Submission timelines: Pre-applications are due by June 20, 2025, with full applications by September 25, 2025. - Funding Limit: Projects are capped at total costs of $4.2 million over a maximum performance period of four years. - Required studies range from initial proof-of-concept trials to phase III trials, with preclinical data required to support applications. No animal studies are permitted. - Research must address one or more specified cancer types, emphasizing relevance to military populations and their health concerns. - The application process is two-step: an initial pre-application followed by a full application for invited candidates, with specific criteria for content and formatting. This funding opportunity underscores the DOD's commitment to advancing cancer research that meets the needs of service members, veterans, and their families.
    Similar Opportunities
    DoD Peer Reviewed Medical Research Program, Clinical Trial Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering a grant opportunity under the Peer Reviewed Medical Research Program (PRMRP) for the fiscal year 2025, specifically for the Clinical Trial Award (CTA). This program aims to support the rapid implementation of clinical trials that can significantly impact the treatment or management of diseases relevant to military health, with a focus on areas such as autoimmune disorders, cardiovascular health, infectious diseases, and neuroscience. Approximately $32 million is available for this initiative, with an expected four awards, each capped at $8 million, and applications are due by July 21, 2025. Interested applicants can reach out to the CDMRP Help Desk at help@eBRAP.org or by phone at 301-682-5507 for further assistance.
    DOD Peer Reviewed Cancer, Idea Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering the fiscal year 2025 Peer Reviewed Cancer Research Program (PRCRP) Idea Award to support innovative cancer research that prioritizes military health. This grant aims to fund high-risk, high-reward proposals that focus on specific cancer types relevant to Service Members, Veterans, and their families, with an emphasis on introducing new paradigms in cancer care and addressing environmental exposure risks. With an estimated total program funding of approximately $14 million, the program anticipates awarding around 25 projects, each with a maximum funding limit of $560,000 for a duration of up to two years. Interested applicants must submit a pre-application by June 20, 2025, followed by a full application due by September 25, 2025; for further inquiries, contact the CDMRP Help Desk at help@eBRAP.org or call 301-682-5507.
    DOD Peer Reviewed Cancer, Impact Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering the FY25 Peer Reviewed Cancer Research Program (PRCRP) Impact Award to support high-impact research aimed at improving clinical cancer care relevant to military health. This grant seeks mature research projects that demonstrate potential for near-term benefits in cancer treatment and patient outcomes, particularly focusing on specific cancer types such as bladder, blood, and brain cancers, while excluding melanoma and breast cancers. The program emphasizes the importance of preliminary data, collaboration with Department of Defense (DOD) and Veterans Affairs (VA) entities, and rigorous study designs to advance cancer detection and treatment for service members and their families. The estimated total program funding is $45.5 million, with individual awards capped at $1.4 million for single Principal Investigator applications and $1.75 million for partnering applications, over a maximum period of three years. Interested applicants must submit a pre-application by September 25, 2025, and can contact the CDMRP Help Desk at help@eBRAP.org for further assistance.
    DoD Prostate Cancer, Clinical Consortium Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering the Fiscal Year 2025 Prostate Cancer Research Program Clinical Consortium Award, aimed at advancing clinical trials for novel therapeutic interventions in prostate cancer. This grant supports the establishment of a consortium of leading researchers across multiple institutions to expedite the clinical advancement of treatments, with a focus on understanding disease progression, improving patient quality of life, and ensuring equitable access to care for high-risk populations. The total estimated funding for this opportunity is approximately $36.8 million, with $12.2 million allocated for one Coordinating Center and $24.6 million for up to eleven clinical research sites, each with specific funding caps and a duration of four years. Interested applicants must submit a pre-application by August 8, 2025, followed by a full application by August 29, 2025; for further inquiries, contact the CDMRP Help Desk at help@eBRAP.org or call 301-682-5507.
    DoD Rare Cancers, Idea Development Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Materiel Command (USAMRAA), is offering a funding opportunity for the Rare Cancers Research Program (RCRP) Idea Development Award for fiscal year 2025. This grant aims to support innovative research that explores new ideas and develops impactful strategies in the area of rare cancers, which are defined as those affecting six or fewer individuals per 100,000 annually in the U.S. Eligible applicants include various organizations, and the program encourages interdisciplinary collaboration among military, academic, and industry sectors to enhance health outcomes for military Service Members, Veterans, and the broader public. The total estimated program funding is $6,860,000, with a funding limit of $490,000 per application. Key deadlines include a pre-application due by July 1, 2025, and a full application by October 6, 2025. For further inquiries, applicants can contact the CDMRP Help Desk at help@eBRAP.org or by phone at 301-682-5507.
    DoD Rare Cancers, Resource and Community Development Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering the FY25 Rare Cancers Research Program Resource and Community Development Award, with an estimated total funding of $5.6 million aimed at enhancing research resources and clinical data related to rare cancers. This grant seeks to address critical gaps in rare cancer research, including the lack of resources, communication strategies, and data-sharing infrastructure, while emphasizing the integration of patient advocates throughout the project lifecycle. Eligible applicants include both domestic and foreign non-profit and for-profit organizations, with applications due by October 6, 2025, following a pre-application deadline of July 1, 2025. For further inquiries, interested parties can contact the CDMRP Help Desk at help@eBRAP.org or by phone at 301-682-5507.
    DoD Rare Cancers, Concept Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the U.S. Army Medical Research Acquisition Activity (USAMRAA), is offering a grant opportunity under the FY25 Rare Cancers Research Program (RCRP) Concept Award, aimed at funding innovative research focused on rare cancers. This program seeks to support groundbreaking, untested studies that can potentially lead to new avenues of investigation in the field, particularly benefiting active-duty service members, veterans, military beneficiaries, and the general public. With an estimated total funding of approximately $2.38 million, individual applications can request up to $140,000, and the performance period for funded projects is capped at two years. Interested applicants must submit a Letter of Intent by July 22, 2025, followed by a full application due by August 26, 2025; for further inquiries, contact the CDMRP Help Desk at help@eBRAP.org or call 301-682-5507.
    DOD Duchenne Muscular Dystrophy, Clinical/Translational Research Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is offering a grant opportunity for the Duchenne Muscular Dystrophy Research Program's Clinical/Translational Research Award (CTRA) for fiscal year 2025. This funding initiative aims to support advanced translational research that accelerates promising ideas in Duchenne muscular dystrophy (DMD) into clinical applications, particularly focusing on therapies effective across all age groups, including infants and nonambulatory individuals. With an estimated total program funding of approximately $8.56 million, the program anticipates awarding around five grants, encouraging collaborations with early-career investigators and requiring applications to include preliminary data relevant to DMD. Interested applicants should note that a pre-application is due by July 25, 2025, with full applications due by August 8, 2025; for further inquiries, contact the CDMRP Help Desk at help@eBRAP.org or call 301-682-5507.
    DOD Ovarian Cancer, Clinical Trial Academy – Early-Career Investigator Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Materiel Command (USAMRAA), is offering the Ovarian Cancer Clinical Trial Academy – Early-Career Investigator Award for Fiscal Year 2025. This grant aims to support early-career investigators in conducting clinical trials focused on ovarian cancer, emphasizing professional development, intensive mentoring, and networking opportunities. The program is critical for enhancing the research landscape in ovarian cancer, with an estimated total funding of approximately $1.4 million available for a maximum of four years. Interested applicants must submit a pre-application by June 12, 2025, followed by a full application due on September 11, 2025, and can reach out to the CDMRP Help Desk at help@eBRAP.org or by phone at 301-682-5507 for further information.
    DoD Toxic Exposures Clinical Trial Partnership Award
    Dept. of the Army -- USAMRAA
    The Department of the Army, through the US Army Medical Research and Development Command (USAMRAA), is inviting applications for the FY25 Toxic Exposures Research Program (TERP) Clinical Trial Partnership Award (CTPA), aimed at supporting collaborative clinical trials focused on health issues related to military-related toxic exposures. The initiative seeks to rapidly implement studies that address the prevention, treatment, and management of diseases or symptoms resulting from such exposures, with an estimated total program funding of $4.2 million available for this purpose. Eligible applicants include a wide range of nonprofit and for-profit organizations, with a requirement for partnerships involving multiple Principal Investigators (PIs) to enhance collaboration and research efficacy. Interested parties should note that the application process involves a two-step submission of a pre-application and full application, with a closing date set for October 16, 2025. For further inquiries, applicants can contact the CDMRP Help Desk at help@eBRAP.org or by phone at 301-682-5507.