The Department of Health and Human Services, through the National Institutes of Health (NIH), announces the IDeA Clinical & Translational Research Network (CTR-N) Award (P50 Clinical Trial Optional). The funding opportunity primarily targets states with historically low NIH funding success rates to enhance biomedical research capacity and support clinical research addressing health challenges in these populations. Eligible organizations, particularly in IDeA-eligible states, can submit one application for up to $3.3 million in annual direct costs over a maximum project period of five years. The CTR-N must be directed by a health research organization with proven clinical research capabilities and include a statewide or multi-state network of partner organizations. The application should feature essential components, including Administrative, Research Design, Community Engagement, Professional Development, and Health Research Cores, which collectively promote collaborative research and workforce development. Additionally, applicants are required to submit a Plan for Enhancing Diverse Perspectives (PEDP) to illustrate strategies for fostering inclusivity in research activities. The application can be submitted via the NIH ASSIST system or through an institutional system-to-system solution. Key dates include an open application date starting October 9, 2023, with the opportunity expiring on October 10, 2025.