The Centers for Disease Control and Prevention (CDC) is offering a cooperative agreement to support sustainable HIV patient and program monitoring systems in Zambia under the President's Emergency Plan for AIDS Relief (PEPFAR). This initiative aims to enhance the capacity of the Zambian Ministry of Health and the Smart Zambia Institute to ensure that digital health information is accessible to stakeholders at all levels, thereby improving accountability and monitoring of health outcomes related to HIV and related conditions. The total estimated funding for the first fiscal year is approximately $30 million, with four awards expected, and applications must be submitted electronically by February 17, 2026, to be considered. For further inquiries, interested applicants can contact the CDC at pepfarfoas@cdc.gov.

The Award Ceiling for Year 1 is 0 (none). CDC anticipates an Approximate Total Fiscal Year Funding amount of $30,000,000 for Year 1, subject to the availability of funds.This Notice of Funding Opportunity (NOFO) will support Government of Zambia&#8217;s national patient and program monitoring systems, in cooperation with the Ministry of Health (MOH) and Smart Zambia Institute (SZI). This NOFO focuses on supporting MOH and SZI capacity, in alignment with PEPFAR&#8217;s goal of transition to host government self-reliance. The overall goal of the NOFO is to assist the Zambian government in its efforts ensure digital information from all health interactions for HIV and related health conditions is available to users, stakeholders, and decision-makers at all levels: facility, district, province, and national. Successful digitization will ensure accountability for resources allocated to health, measure individual and population level health outcomes, and allow the host government to monitor the cost-effectiveness of HIV and related programs. A key focus of this NOFO is to support the Government of Zambia to transform current health information systems to make them more resilient and require fewer resources, both human and financial, for sustainability, leveraging technology innovations to simplify patient and program monitoring processes and facilitate improved data access, quality, and use. You will be responsible for engaging MOH, SZI, and other stakeholders, to ensure fill oversight of all health information systems, and related data, by the Government of Zambia.

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