NIDCR Prospective Observational or Biomarker Validation Study Cooperative Agreement

The National Institutes of Health (NIH) is announcing a forthcoming opportunity for a cooperative agreement focused on prospective observational or biomarker validation studies through the National Institute of Dental and Craniofacial Research (NIDCR). This initiative aims to solicit applications for studies that involve the prospective collection or continued analysis of data and biospecimens, with an emphasis on well-designed clinical studies that can enhance understanding and improve dental, oral, and craniofacial health. Such studies are crucial for assessing exposure and its relationship to disease development, as well as validating biomarkers for diagnosis and treatment response. While applications are not currently being accepted, interested investigators are encouraged to prepare collaborative proposals in anticipation of the opportunity, which is expected to be formally announced in November 2025, with a closing date for submissions in February 2026. For further inquiries, potential applicants can contact Dr. Lorena Baccaglini at lorena.baccaglini@nih.gov or by phone at 301-435-7908.