65--Single Cell RNA Sequencing Kits for NICHD Thyroid
ID: 75N94024Q00213Type: Presolicitation
Overview

Buyer

HEALTH AND HUMAN SERVICES, DEPARTMENT OFNATIONAL INSTITUTES OF HEALTHNATIONAL INSTITUTES OF HEALTH NICHDBETHESDA, MD, 20817, USA

NAICS

In-Vitro Diagnostic Substance Manufacturing (325413)

PSC

IN VITRO DIAGNOSTIC SUBSTANCES, REAGENTS, TEST KITS AND SETS (6550)
Timeline
    Description

    The National Institutes of Health, National Institute of Child Health and Development (NICHD) plans to award a contract for Single Cell RNA Sequencing Kits to support thyroid hormone studies. This is a pre-solicitation notice, with the intent to award the contract without competition to 10X GENOMICS, INC.

    The NICHD invites capable and interested parties to submit responses outlining their qualifications and capacity to fulfill the requirement. The agency will consider the information received but maintains discretion on whether to proceed competitively or non-competitively.

    The opportunity seeks to procure single-cell RNA sequencing kits for research purposes. Respondents should have the capability to provide the required sequencing kits and ensure compliance with the specialized needs of thyroid hormone studies.

    To participate, interested parties must register in the System for Award Management (SAM) and submit their responses by the deadline. The primary contact for this opportunity is Jacob Balenson, whose email is provided in the listing.

    Please note that responses must be submitted electronically, following the specified format and deadline.

    Point(s) of Contact
    Files
    No associated files provided.
    Lifecycle
    Title
    Type
    Similar Opportunities
    Short-Read Next-Generation DNA Sequencing System
    Active
    Health And Human Services, Department Of
    The Department of Health and Human Services, specifically the National Institutes of Health (NIH), is seeking quotations for a Short-Read Next-Generation DNA Sequencing System to enhance its laboratory capabilities for rare variant discovery. The system must meet stringent requirements, including high accuracy (≥90%), compatibility with existing library formats, and the ability to detect variants down to 0.001%, along with specific physical dimensions and training for researchers. This procurement is crucial for advancing scientific research capabilities within the NIH and will be processed under Simplified Acquisition Procedures, with no set-aside for small businesses. Interested vendors should submit their quotes, including pricing and compliance with technical specifications, to Matt Lear at matt.lear@nih.gov by the specified deadline.
    Next-Generation Sequencing (NGS) Liquid Handling Systems – Brand Name or Equal
    Active
    Health And Human Services, Department Of
    The Department of Health and Human Services, specifically the National Institutes of Health (NIH), is seeking quotes for two Next-Generation Sequencing (NGS) Liquid Handling Systems to enhance research capabilities at its Bethesda, Maryland campus. These systems are essential for high-throughput processing in infectious disease research, particularly for single cell-based antibody discovery and RNA/DNA processing, which are critical for pandemic preparedness. Interested vendors must submit their quotes by 12:00 pm EST on September 26, 2024, including detailed specifications and compliance with federal regulations, to Daveta H. Brown at daveta.brown@nih.gov.
    NIEHS - Exodus H-600
    Active
    Health And Human Services, Department Of
    The National Institute of Environmental Health Sciences (NIEHS) intends to negotiate a sole-source contract with Exodus Bio, Inc. for the acquisition of an Exodus H-600 automatic exosome isolation system. This procurement aims to enhance the NIEHS's capabilities in biological product manufacturing, specifically focusing on the isolation of exosomes, which are critical for various research applications in environmental health. The contract, associated with NAICS Code 325414, is expected to include one unit of the specified equipment, with a delivery timeframe of 60 days post-award. Interested parties capable of fulfilling this requirement are encouraged to submit a capability statement via email by September 18, 2024, and inquiries can be directed to Tanya Redfearn at shields3@niehs.nih.gov or by phone at 984-287-3052.
    SOURCES SOUGHT: Maintenance and Repair Service for the Nanopore Promethion Long Read Sequencer
    Active
    Health And Human Services, Department Of
    The Department of Health and Human Services, specifically the National Institutes of Health (NIH), is seeking qualified vendors to provide maintenance and repair services for the Nanopore Promethion Long Read Sequencer. The primary objective is to ensure the reliable functioning of this critical laboratory equipment, which supports ongoing research at the National Institute on Aging, particularly in neurogenetics and Alzheimer's disease studies. The selected contractor will be responsible for preventative maintenance, software upgrades, and troubleshooting, with a requirement for OEM-certified parts and factory-trained technicians. Interested parties must submit their capability statements to Hashim Dasti at hashim.dasti@nih.gov by September 18, 2024, at 11 AM Eastern Time, adhering to specified formatting guidelines.
    Qiagen Real Time Semi-Quantitative PCR (RT-qPCR) and Digital PCR (dPCR) System or Equal
    Active
    Health And Human Services, Department Of
    The Department of Health and Human Services, specifically the National Institutes of Health (NIH), is seeking proposals for a Qiagen Real Time Semi-Quantitative PCR (RT-qPCR) and Digital PCR (dPCR) System or an equivalent product. The procurement aims to support research into neurodegenerative diseases and retroviral infections, requiring a system with multiplex capability for detecting five gene targets, automated operation, low variability in results, and a compact size not exceeding 16” x 28” x 20”. Proposals must be submitted by 9:00 a.m. Eastern Time on September 17, 2024, and should include a completed copy of certain FAR clauses and the Unique Entity ID. For further inquiries, interested parties can contact Frederick Weddington at frederick.weddington@nih.gov or by phone at 301-594-6835.
    ThermoFisher branded Invitrogen ProcartaPlex immunoassay kits (Brand Name restriction)
    Active
    Health And Human Services, Department Of
    The Department of Health and Human Services, specifically the National Institutes of Health (NIH), is seeking quotes for ThermoFisher branded Invitrogen ProcartaPlex immunoassay kits as part of a combined synopsis/solicitation. The procurement aims to acquire specific immunoassay kits necessary for testing human cytokine and chemokine levels in serum and saliva samples from individuals with alcohol use disorder, which is critical for ongoing research into the effects of alcohol consumption on health. The required kits must be capable of detecting and quantifying a panel of 80 targets simultaneously and are essential for ensuring continuity and comparability across various studies conducted by the NIH Clinical Center. Interested vendors must submit their offers by September 17, 2024, to Lu Chang at lu-chang.lu@nih.gov, including pricing and delivery timelines, as late submissions will not be considered.
    Determining Kinases Inhibition by GSK3 Inhibitors
    Active
    Health And Human Services, Department Of
    The Department of Health and Human Services, specifically the National Institutes of Health (NIH), is seeking a contractor to determine kinase inhibition by GSK3 inhibitors as part of a non-competitive procurement process. The objective is to generate 5,000 data points and 400 IC50 curves through biochemical assays to support research on CTNNB1 syndrome, a rare neurodevelopmental disorder, by profiling the efficacy of newly developed compounds against human lipid kinases. This project is crucial for advancing treatment strategies and optimizing compound design, with a contract anticipated to be awarded by September 17, 2024. Interested parties should direct inquiries to Michelle Cecilia at michelle.cecilia@nih.gov, and must ensure compliance with federal regulations as outlined in the attached documents.
    Brand-Name or Equal Axion Biosystems 48-well microelectrode array plates for the National Center for Advancing Translational Sciences
    Active
    Health And Human Services, Department Of
    The National Institutes of Health (NIH) is seeking proposals for the procurement of Axion Biosystems 48-well microelectrode array plates, specifically the CytoView MEA 48 model, as part of a project aimed at evaluating the safety of antisense oligonucleotides in neurological treatments. The acquisition includes 10 boxes of these plates, which are crucial for conducting neurotoxicity screening assays by recording neuronal electrical signals, thereby facilitating both acute and chronic toxicity assessments. Interested vendors must submit their quotations by 4:00 PM EDT on September 9, 2024, to the Contracting Officer, Mark McNally, at mark.mcnally@nih.gov, with the anticipated award date set for September 12, 2024. The procurement is expected to follow simplified acquisition procedures, with no set-aside restrictions, and the total price must encompass all shipping and handling costs.
    Notice of Intent - Ortho Clinical Reagents and Supplies
    Active
    Health And Human Services, Department Of
    The National Institutes of Health (NIH) intends to award a fixed-price contract for Ortho Clinical reagents and supplies, specifically for the Department of Transfusion Medicine at the NIH Clinical Center in Bethesda, Maryland. This procurement aims to secure essential analyzer supplies and reagents that are critical for ensuring the safety and effectiveness of blood products used in transfusion therapy, which must meet specific compatibility requirements for patient treatment. The selected supplier, Ortho-Clinical Diagnostics, Inc., is the sole source for these unique reagents, which have undergone extensive validation studies and are necessary for compatibility testing of both patients and blood donors. Interested parties capable of providing similar products may submit a capability statement by September 22, 2024, to Sheri Eiri at sheri.eiri@nih.gov, as the contract is contingent upon the availability of FY2025 funding.
    Using humanized mouse models of NNMT and SULT1A1 for follow-up efficacy studies
    Active
    Health And Human Services, Department Of
    The Department of Health and Human Services, through the National Institutes of Health (NIH) and its National Center for Advancing Translational Sciences (NCATS), intends to award a sole-source contract to GemPharmatech, LLC for follow-up efficacy studies utilizing humanized mouse models of NNMT and SULT1A1. The primary objective of this procurement is to conduct a series of studies, including a Maximum Tolerated Dose (MTD) study, a pharmacokinetic (PK) study, and an efficacy study, to evaluate small molecule inhibitors developed by NCATS, necessitating the creation of mouse models that express human versions of the enzymes involved. This research is critical for advancing the development of therapeutics targeting various human diseases, and the project is expected to span 12 months. Interested parties may submit their capabilities by September 17, 2024, to Michelle Cecilia at michelle.cecilia@nih.gov, with the contract value and specific funding details not disclosed in the announcement.