Groundbreaking Lymphatic Interventions and Drug Exploration (GLIDE) Proposers' Day
ID: ARPA-H-SN-24-112Type: Special Notice
Overview

Buyer

HEALTH AND HUMAN SERVICES, DEPARTMENT OFNATIONAL INSTITUTES OF HEALTHNIH ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H)Bethesda, MD, 208920004, USA

NAICS

Research and Development in Biotechnology (except Nanobiotechnology) (541714)

PSC

HEALTH R&D SERVICES; HEALTH CARE SERVICES; EXPERIMENTAL DEVELOPMENT (AN13)

Original Source

https://sam.gov/opp/5d0e78b1d6a34fe49becaeaae7660ec9/view
Timeline
    Description

    The Department of Health and Human Services, through the National Institutes of Health's Advanced Research Projects Agency for Health (ARPA-H), is hosting a Proposers' Day for the Groundbreaking Lymphatic Interventions and Drug Exploration (GLIDE) Program. This hybrid event, scheduled for October 1, 2024, in Nashville, Tennessee, aims to inform potential proposers about the program's objectives, which focus on transforming treatments for lymphatic dysfunction through innovative physical interventions and therapeutics. Participation in the Proposers' Day is optional but encouraged, providing an opportunity for networking and collaboration, with registration opening on July 31 and closing on September 24, 2024. Interested parties can contact the GLIDE Team at GLIDE@arpa-h.gov for further information.

    Point(s) of Contact
    The GLIDE Team
    GLIDE@arpa-h.gov
    Files
    Title
    Posted
    GLIDE SN - July 31 2024.pdf
    The Advanced Research Projects Agency for Health (ARPA-H), through its Health Science Futures (HSF) Office, is preparing to launch the Groundbreaking Lymphatic Interventions and Drug Exploration (GLIDE) program. This special notice announces an upcoming Proposers' Day on September 17, 2024, in Memphis, Tennessee, to introduce the program and encourage potential proposers to participate. The primary objective of the GLIDE program is to revolutionize the treatment of primary lymphatic diseases (LD) and common chronic diseases associated with lymphatic dysfunction. Currently, patients suffering from these conditions have limited therapeutic options, mostly palliative in nature. ARPA-H aims to develop an array of innovative treatments that address the underlying causes of lymphatic dysfunction, offering cures or, at the very least, significant relief and stabilization of the disease. The program will focus on two main areas: physical interventions to restore lymphatic flow and normalize function, and targeted pharmacologic, gene, and cell therapies. The GLIDE program seeks to make these treatments widely accessible and adoptable by the healthcare community, benefiting hospitals, doctors, and patients alike. While the special notice does not constitute a formal solicitation, it serves as an important precursor, providing potential proposers with an understanding of the program's scope and objectives, as well as offering opportunities for collaboration and team formation. The subsequent release of the Innovative Solutions Opening (ISO) will provide the full programmatic details and initiate the formal proposal submission process.
    GLIDE SN August 16 Mod.pdf
    The ARPA-H Special Notice (SN) ARPA-H-SN-24-112 details the Proposers’ Day Announcement for the groundbreaking GLIDE Program focused on lymphatic interventions and drug exploration. Scheduled for October 1, 2024, in Nashville, Tennessee, this hybrid event aims to inform potential proposers about the program's goals, scope, and collaborative opportunities. Attendance is optional but encouraged, providing a platform for networking and team formation. The GLIDE Program aims to transform treatments for lymphatic dysfunction, exploring physical interventions and therapeutics to alleviate symptoms for patients with chronic and primary lymphatic diseases. The document outlines submission guidelines for proposals, including an optional poster session and lightning talks to facilitate collaboration, as well as a "teaming profile" form for interested parties. Registration is required, opening on July 31 and closing on September 24, 2024. The notice emphasizes that participation in the Proposers’ Day is not mandatory for proposal submission and serves only as an informative and collaborative event. Additionally, attendees must register in advance, and the document clarifies the nature of this SN as an informational communication, not a solicitation for solutions. Overall, this initiative demonstrates ARPA-H's commitment to advancing equitable healthcare outcomes through innovative lymphatic research and therapies.
    GLIDE SN August 9 Mod.pdf
    The Advanced Research Projects Agency for Health (ARPA-H) is hosting a Proposers' Day for its newly approved GLIDE program. GLIDE aims to develop treatments targeting abnormal lymphatic structure and function, revolutionizing healthcare outcomes. This optional event on September 17th in Nashville, Tennessee, will provide potential proposers with program details, fostering collaborations and teaming opportunities. It will include sessions on program goals, expectations, and contracting, as well as poster and lightning talk presentations. ARPA-H encourages attendance to explore the program's mission and form teams, but participation is not mandatory for future submissions. Registration is required and will be accepted on a first-come, first-served basis. Key information and FAQs will be made available on ARPA-H's website. This Special Notice is for planning purposes only; participation is voluntary, and ARPA-H will not reimburse costs incurred.
    Lifecycle
    Title
    Type
    Groundbreaking Lymphatic Interventions and Drug Exploration (GLIDE) Proposers' Day
    Currently viewing
    Special Notice
    Similar Opportunities
    Industry Day - Doing Business With ARPA-H
    Active
    Health And Human Services, Department Of
    The Advanced Research Projects Agency for Health (ARPA-H), part of the Department of Health and Human Services, is hosting a virtual "Doing Business With ARPA-H" industry day event on November 13, 2024. This event aims to engage various stakeholders, including businesses, nonprofit organizations, and academic institutions, to provide insights into ARPA-H’s mission, current research and development (R&D) initiatives, and contracting processes. The event is crucial for fostering partnerships and enhancing understanding of funding opportunities within the health ecosystem, ultimately supporting the agency's goal of advancing health innovations. Interested parties must pre-register by November 8, 2024, and can direct inquiries to DBWA@arpa-h.gov for further information.
    DRAFT Decentralized Engineering of Cells Informed by Dynamic Evidence (DECIDE) Exploration Topic
    Active
    Health And Human Services, Department Of
    The Department of Health and Human Services, through the National Institutes of Health's Advanced Research Projects Agency for Health (ARPA-H), is soliciting proposals for the Decentralized Engineering of Cells Informed by Dynamic Evidence (DECIDE) exploration topic. This initiative aims to enhance access to curative cell therapies for pediatric patients with rare genetic diseases by developing novel quality assurance mechanisms at Academic Medical Centers (AMCs) over a structured 24-month program. The program will focus on identifying manufacturing variability, improving batch quality through signature identification methodologies, and creating statistical tools to guide production decisions, ultimately streamlining the development of small batch autologous cell therapies. Proposals are due by October 22, 2024, and interested parties should direct inquiries to the designated email address provided in the solicitation.
    PREDICTIONS FOR REAL-TIME OPTIMIZATION OF MICROBIOMES OF BUILT ENVIRONMENTS (PRO-MICROBE) EXPLORATION TOPIC
    Active
    Health And Human Services, Department Of
    The Department of Health and Human Services, through the National Institutes of Health's Advanced Research Projects Agency for Health (ARPA-H), is soliciting proposals for the "Predictions for Real-time Optimization of MICRObiomes of Built Environments" (PRO-MICROBE) exploration topic. This initiative aims to develop predictive models that enhance indoor microbiome health by creating a microbiome health index to assess the impact of indoor microbial communities on occupant health. The program is significant for improving public health, particularly in socio-economically disadvantaged communities, by promoting environments that support beneficial microbial communities while mitigating pathogenic risks. Proposals are due by November 4, 2024, and must be submitted through the designated ARPA-H portal, with multiple awards anticipated based on the quality of submissions. For inquiries, applicants can reach out via the provided ARPA-H contact link.
    Module Announcement; Universal PatchinG and Remediation for Autonomous DEfense (UPGRADE)
    Active
    Health And Human Services, Department Of
    The Department of Health and Human Services, through the National Institutes of Health's Advanced Research Projects Agency for Health (ARPA-H), is soliciting proposals for the Universal Patching and Remediation for Autonomous Defense (UPGRADE) program, aimed at enhancing cybersecurity in U.S. hospitals. This initiative seeks to develop an integrated cybersecurity platform that automates vulnerability detection and remediation processes, thereby enabling hospital IT teams to protect critical medical devices from cyber threats without requiring additional personnel. Given the increasing frequency of cyberattacks on healthcare facilities, the UPGRADE program is crucial for ensuring the continuity of patient care and operational resilience in complex hospital environments. Proposals are due by 12:00 PM ET on October 2, 2024, and interested parties should direct inquiries to ARPA-H Solutions via their website.
    POSEIDON (Platform Optimizing SynBio for Early Intervention and Detection in ONcology)
    Active
    Health And Human Services, Department Of
    The Department of Health and Human Services, through the National Institutes of Health's Advanced Research Projects Agency for Health (ARPA-H), is soliciting proposals for the POSEIDON program, which focuses on developing advanced at-home Multi-Cancer Early Detection (MCED) tests using synthetic biology. The program aims to create low-cost, accessible tests for the early-stage identification of over 30 solid tumors, utilizing breath and urine samples, with an emphasis on integrating these tests with telehealth systems and ensuring accessibility for underserved populations. This initiative is critical for transforming cancer diagnostics, potentially saving millions of lives and reducing the economic burden of late-stage cancer care, with a target commercialization price of $100 or less. Interested parties must submit their Solution Summaries by November 6, 2024, with a priority submission date of October 16, 2024, and can contact the POSEIDON Team at POSEIDON@arpa-h.gov for further information.
    HEalth care Rewards to Achieve Improved OutcomES (HEROES)
    Active
    Health And Human Services, Department Of
    Solicitation from the Department of Health and Human Services, Department of Health and Human Services, National Institutes of Health, NIH Advanced Research Projects Agency for Health (ARPA-H) is seeking proposals for the HEalth care Rewards to Achieve Improved OutcomES (HEROES) program. This program aims to improve the health status of communities by incentivizing community-based interventions to achieve positive health outcomes in specific patient populations. The program focuses on four specific health outcome categories: reduction in intrapartum and postpartum severe obstetric complications, reduction in the aggregate 10-year risk of heart attack and stroke, reduction in the rate of emergency medical services (EMS) patient encounters for opioid overdoses, and reduction in the rate of EMS patient encounters for alcohol-related emergencies. Proposers can select one of the four health outcome categories in geographic areas ranging from 500,000 to 5 million people in the general population. Solution summaries must be submitted in advance of a full proposal, and separate solution summaries and proposals are required for each outcome category/geographic area pairing. All submissions and questions should be directed to the provided ARPA-H Ask-A-Question and submission links.
    Office-Wide Innovative Solutions Opening for Proactive Health Office (PHO)
    Active
    Health And Human Services, Department Of
    Solicitation from the Department of Health and Human Services, National Institutes of Health, seeks innovative solutions for the Proactive Health Office (PHO). The PHO aims to improve the healthspan and health outcomes of Americans before the onset of disease and diminished quality of life. The PHO is specifically interested in population-level improvements in disease prevention and wellness-promoting behaviors, as well as the development of early-detection methods and prophylactic interventions. System level innovations for effective delivery of proactive health are also sought. Solution summaries, questions, and proposal submissions should be made through the ARPA-H website.
    Performance and Reliability Evaluation for Continuous modIfications and uSEability of AI (PRECISE-AI)
    Active
    Health And Human Services, Department Of
    The Department of Health and Human Services, through the National Institutes of Health's Advanced Research Projects Agency for Health (ARPA-H), is seeking proposals for the Performance and Reliability Evaluation for Continuous Modifications and Usability of AI (PRECISE-AI) program. This initiative aims to develop self-correction techniques for AI decision support tools (AI-DSTs) in healthcare, addressing the need for ongoing efficacy and safety monitoring beyond pre-market evaluations. The program is critical as it responds to the rapid integration of AI technologies in healthcare, ensuring that these tools remain effective and trustworthy in diverse clinical settings. Interested parties are encouraged to submit questions regarding the draft solicitation, and further details, including a Proposers' Day, will be announced. For inquiries, contact the PRECISE-AI Coordinator at PRECISEAI@arpa-h.gov.
    Office-Wide Innovative Solutions Opening for Health Science Futures (HSF)
    Active
    Health And Human Services, Department Of
    Presolicitation notice from the HEALTH AND HUMAN SERVICES, DEPARTMENT OF, NATIONAL INSTITUTES OF HEALTH, NIH ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H) is seeking innovative solutions through individual Office-wide solicitations. The Office-wide ISOs will target specific areas of interest and may request abstracts and/or proposals. The goal is to select revolutionary ideas to improve health outcomes for all Americans. The solicitation will award Other Transactions and Cooperative Agreements, making the Federal Acquisition Regulations (FAR) not applicable. This notice includes DRAFT Office-wide ISOs for each ARPA-H Mission Office (HSF, PHO, RSO, and SSO). Questions regarding the DRAFT solicitations should be submitted through the provided link.
    Discover DSO Day (D3)
    Active
    Dept Of Defense
    The Defense Advanced Research Projects Agency (DARPA) is opening up its Defense Sciences Office (DSO) mission and funding opportunities to external participants. Non-traditional proposers are especially invited to attend the upcoming Discover DSO Day (D3) event. The main objectives are to create awareness about DSO's mission and funding opportunities and facilitate discussions between participants and DSO program managers. The event will take place in person on October 3-4, 2024, in Boston, MA, and will include presentations, panels, and networking sessions. The focus is on exploring revolutionary ideas and technologies with potential national security applications. DSO's research interests are wide-ranging, encompassing fields such as high-energy physics, cognition, computation, sensing, and novel materials. This special notice is not a solicitation, but rather a precursor to potential funding opportunities. DARPA aims to foster innovation by engaging a diverse range of attendees, including U.S. citizens, permanent residents, and eligible foreign nationals. Participants must register and pay a fee of $125 for the first day and $75 for the second day to attend. For more information and to register, interested parties should visit the registration website, which provides further details and important deadlines. DARPA encourages potential applicants to seize this opportunity to gain insights into the proposal process and explore potential collaborations. If you require further information, you can contact the BAA Coordinator at discoverdsoday2024@darpa.mil.