NASA Johnson Space Center (JSC) is seeking hypobaric chamber services to support the development of the Aerospace Estimation Tool for Hypobaric Exposure Risk (AETHER), a decompression sickness (DCS) risk estimation tool. This Statement of Work (SOW) outlines the need for facilities to recruit six subjects to participate in control and two experimental prebreathe conditions, simulating extravehicular activities (EVAs). The study investigates the effects of exercise during prebreathe as a DCS mitigation strategy, with data informing future space vehicle and mission requirements. Facilities must have proven capabilities, including prior pilot chamber test completion and resolution of any identified deficiencies. The procurement is firm fixed price, and facilities are responsible for subject recruitment, screening (including VO2pk testing and PFO assessment), data collection, and data delivery to NASA. NASA will provide protocols, conduct analysis, and coordinate meetings and training. Strict medical monitoring, EVA simulation procedures, and data reporting requirements are detailed, emphasizing safety and data quality. Facilities will also be responsible for procuring most hardware and ensuring staff proficiency in various operational aspects, including mask operating procedures and dangerous goods shipping.

NASA's Request for Quotation (RFQ) 80NSSC26920179Q-1 seeks