The National Aeronautics and Space Administration (NASA) is seeking partners for its Payloads and Research Investigations on the Surface of the Moon (PRISM) initiative, aimed at developing and flying science-driven instruments and technology demonstration payloads for lunar missions. The opportunity invites non-Government entities to collaborate with NASA Glenn Research Center (GRC) in preparing proposals that align with the scientific goals of various NASA directorates, including Planetary Science, Earth Science, and Astrophysics, among others. This initiative is crucial for advancing lunar exploration and commercial development, with payloads to be delivered via Commercial Lunar Payload Services (CLPS) landers to specified lunar locations. Interested parties must submit their responses, limited to two pages, detailing their capabilities and relevant experience by December 5, 2025, to Hunter Butkovic at hunter.c.butkovic@nasa.gov, with questions due by December 3, 2025.