The National Institute of Child Health and Development (NICHD), in collaboration with the National Institute of Diabetes, Digestive, and Kidney Disease (NIDDK), intends to contract with GraphPad Software, LLC for the renewal of 500 subscriptions of GraphPad Prism software. This decision is justified under the Federal Acquisition Regulation (FAR) as a non-competitive procurement due to GraphPad being the sole provider of the software. The renewal period is set for April 8, 2025, to April 7, 2026, following an earlier purchase of 800 licenses in March 2024. GraphPad Prism is essential at NIH for its biostatistical analysis, curve fitting, and scientific graphing capabilities, widely utilized by research institutions and pharmaceutical companies. The acquisition, not exceeding $250,000, falls under FAR’s Simplified Acquisition Procedures, allowing for this streamlined process. Interested vendors may respond to this notice to indicate their capabilities, but the government retains discretion over whether to entertain competitive offers. This non-competitive approach reflects an identified need for continued access to the software to ensure the accuracy and efficiency of scientific data analysis within NIDDK.