The National Institutes of Health (NIH), specifically the National Institute of Allergy and Infectious Diseases (NIAID), intends to negotiate a sole source contract for the MetaOx, an optical monitor of metabolic rate of oxygen consumption, with ISS Medical, Inc. This procurement aims to acquire a demonstration unit with an option to purchase, which is critical for measuring various physiological parameters such as cerebral tissue hemoglobin concentration and microvascular cerebral blood flow, particularly in clinical applications for infants, children, and adults. Interested vendors must submit a capability statement addressing specific requirements by 2:00 PM EST on September 13, 2024, via the NIAID electronic Simplified Acquisition Submission System (eSASS), with all submissions subject to the guidelines outlined in FAR 52.212-1(f). For further inquiries, vendors can contact Rubyanne Matthews at rubyanne.matthews@nih.gov or Jesse Weidow at jesse.weidow@nih.gov.