HTRF® cAMP Gs Dynamic Assay Kit Brand Name or Equal for NCATS
ID: 75N95024Q00072Type: Sources Sought
Overview

Buyer

HEALTH AND HUMAN SERVICES, DEPARTMENT OFNATIONAL INSTITUTES OF HEALTHNATIONAL INSTITUTES OF HEALTH NIDABethesda, MD, 20892, USA

PSC

DRUGS AND BIOLOGICALS (6505)

Original Source

https://sam.gov/opp/72818cee795646f08190e70ee66ac960/view
Timeline
  1. 1
    Posted Dec 12, 2023 7:29 PM
  2. 2
    Updated Dec 13, 2023 6:39 PM
  3. 3
    Due Dec 20, 2023 4:00 PM
Description

Sources Sought Notice: HEALTH AND HUMAN SERVICES, DEPARTMENT OF, NATIONAL INSTITUTES OF HEALTH is seeking HTRF® cAMP Gs Dynamic Assay Kit Brand Name or Equal for NCATS. This kit is used to measure Gs coupled receptors and will be used to screen the Tox21 10K library in a high-throughput format. The purpose is to identify a group of G protein-coupled receptors (GPCR) for better biological response space coverage and toxicity prediction. The kit must meet specific physical and functional characteristics and the contractor must deliver within 4 weeks after receipt of order. Interested companies should submit their capability statements addressing the project requirements. The response must be submitted by Tuesday, December 26, 2023, 9:00 AM, Eastern Time.

Point(s) of Contact
Nick Niefeld
(301) 827-2094
nick.niefeld@nih.gov
Files
No associated files provided.
Lifecycle
Title
Type
HTRF® cAMP Gs Dynamic Assay Kit Brand Name or Equal for NCATS
Currently viewing
Sources Sought
Similar Opportunities
Detection of global proteins and mRNA in postnatal heart targeted AdCy8 overexpression mouse strain
Active
Health And Human Services, Department Of
Sources Sought HEALTH AND HUMAN SERVICES, DEPARTMENT OF Detection of global proteins and mRNA in postnatal heart targeted AdCy8 overexpression mouse strain This notice is a Sources Sought notice issued by the NATIONAL INSTITUTES OF HEALTH NIA, under the NATIONAL INSTITUTES OF HEALTH, to determine the availability and capability of qualified sources for a potential requirement. The purpose of this project is to study postnatal protein expression and mRNA signals in AC8 models in order to elucidate their pathways and mechanisms in heart cell survival, cell renewal, and cell mitosis and its regulation. The project requirements include method development and testing of Immuno precipitation (IP), MS analysis, and mRNA seq. The anticipated period of performance is within 90 days after receipt of samples. Small businesses are encouraged to respond. Interested companies should submit documentation of their ability to meet the project requirements to the Contracting Officer. The response must be received by August 6, 2024, at 4:00 pm Eastern Time.
Brand Name or Equal: BMG Labtech VANTAstar-F Plate Reader
Active
Health And Human Services, Department Of
The National Cancer Institute (NCI) is exploring capabilities and interest in the marketplace for a potential future contract related to brand name or equal laboratory equipment. Specifically, they seek information on businesses that can supply a BMG Labtech VANTAstar-F Plate Reader or an equivalent solution. This is a sources sought notice, indicating that no solicitation is currently available, but responses will help determine the most appropriate acquisition method. The NCI aims to identify small businesses that can meet their requirements for this specialized equipment used in measuring and controlling devices. Interested parties are invited to respond with a maximum 10-page written submission, clearly detailing their ability to fulfill the NCI's needs. The information sought in the responses will assist in deciding the acquisition approach and whether a small business set-aside is feasible. Any submitted information must be non-proprietary, as the NCI reserves the right to use it in future solicitations. Responses are due by 10:00 A.M. EST on Monday, July 29, 2024, and should be sent to the contract specialist whose contact details are provided in the attached document. This is a competitive process, and businesses should expect a high level of competition for this potential opportunity. The NCI is under no obligation to issue a contract or respond to submissions. However, if a requirement formalizes, a solicitation may be published, with responses to this notice given precedence for a small business set-aside consideration. For any clarifications or questions, interested parties may contact John Russell or Reyes Rodriguez, whose email addresses are provided in the notice.
Sources Sought Notice: Amplifiers and digitizers for use in electrophysiology experiments
Active
Health And Human Services, Department Of
Sources Sought Notice: Amplifiers and digitizers for use in electrophysiology experiments The Department of Health and Human Services, Department of, National Institutes of Health, National Institutes of Health NIDA, has issued a Sources Sought notice for the procurement of amplifiers and digitizers. These equipment will be used for examining the cellular excitability of neurons located in the midbrain dopamine system and basal ganglia. The amplifiers must have external trigger command or user-programmable voltage threshold for rapid, automatic mode-switching between current and voltage-clamp. They should also be able to detect current or voltage oscillations and automatically disable or reduce compensation settings to protect the cell from damage. Additionally, the amplifiers must include a dual headstage system to record simultaneously in two independent channels and have computer control software for automation of various functions. The digitizers must be compatible with pClamp software and have the ability to sample at 500 kHz per channel. They should also have a humsilencer to eliminate line-frequency noise and be a low-noise data acquisition system with adaptive noise cancellation. The contractor will be required to provide a warranty for the equipment for a period of twelve (12) months from the date of installation, inspection, and acceptance by the Government. Delivery of the equipment should be completed within six (6) months after receipt of order. Interested companies are encouraged to submit a capability statement addressing each of the project requirements, including the total number of employees, professional qualifications of personnel, and any relevant government-wide acquisition contracts. The response should also include the company's name, Unique Entity ID from SAM.gov, physical address, and point of contact information. Small businesses are particularly encouraged to respond. The response must be submitted electronically to the Contract Specialist and Contracting Officer by July 30, 2024, 5 pm Eastern Time. Please note that this notice is for research and information purposes only, and no award will be made as a result of this notice. The Government will not be responsible for any costs incurred by respondents.
Small Business Sources Sought: Amplifiers and digitizers for use in electrophysiology experiments
Active
Health And Human Services, Department Of
Sources Sought: Amplifiers and digitizers for use in electrophysiology experiments The Department of Health and Human Services, Department of, National Institutes of Health, National Institutes of Health NIDA, has issued a Sources Sought notice for the procurement of amplifiers and digitizers. These equipment will be used in electrophysiology experiments to examine the cellular excitability of neurons located in the midbrain dopamine system and basal ganglia. The purpose of this requirement is to acquire the necessary equipment to support research in the Cellular Neurophysiology Section (CNS) focused on the circuit and cellular properties of neurons. Specifically, the CNS is interested in understanding how synaptic and intrinsic conductances expressed on dopamine neurons differ among subpopulations, particularly calcium permeable conductances such as voltage-gated calcium channels and glutamate-activated receptors. This research aims to provide insight into why dopamine neurons in the substantia nigra pars compacta (SNc) are particularly vulnerable in Parkinson's disease. The project requires two amplifiers and two digitizers that meet specific requirements. The amplifiers must have features such as external trigger command, automatic mode-switching between current and voltage-clamp, and the ability to detect and protect the cell from damage. The digitizers must be compatible with pClamp software, sample at 500 kHz per channel, and have a humsilencer to eliminate line-frequency noise. The contractor will be responsible for delivering and installing the equipment within six months after receipt of the order. A warranty period of twelve months from the date of installation, inspection, and acceptance is required. Interested companies should submit a capability statement addressing each project requirement, including the total number of employees, professional qualifications of personnel, and any relevant government-wide acquisition contracts. The response must include the company's name, Unique Entity ID from SAM.gov, physical address, and point of contact information. Responses must be submitted electronically to the Contracting Officer by July 30, 2024, 5 pm Eastern Time. The Government reserves the right to use the information provided for any necessary purposes and may publish a presolicitation synopsis and solicitation in www.sam.gov. Please ensure your response is complete and sufficiently detailed to demonstrate your qualifications for the work.
Integrated Cage Promethion Metabolic System (or Equal).
Active
Health And Human Services, Department Of
Title: Integrated Cage Promethion Metabolic System (or Equal) The Department of Health and Human Services, Department of National Institutes of Health, is seeking an Integrated Cage Promethion Metabolic System (or Equal). This procurement is for a commercial service and is expected to exceed the simplified acquisition threshold. The Integrated Cage Promethion Metabolic System is a metabolic and behavioral phenotyping system used for scientific research. It is a customizable system that includes programmable light intensity and a broad temperature range, allowing for experiments with rodents. The system is designed to be user-friendly, with pull-out shelving for easy installation and access to rodents, as well as effortless cleaning. The desired system is the Promethion Core System or an equivalent. The delivery of the system is expected to be 14 weeks after receipt of order, with the place of delivery and acceptance being 251 Bayview Blvd, Baltimore, Maryland 21224. Interested parties must submit their quotations electronically to Iris Merscher, Contract Specialist, at iris.merscher@nih.gov by 5:00 p.m., Eastern Daylight Time on August 5, 2024. The solicitation number is 75N95024Q00298.