Detection of global proteins and mRNA in postnatal heart targeted AdCy8 overexpression mouse strain
ID: 75N95024R00109Type: Combined Synopsis/Solicitation
Overview

Buyer

HEALTH AND HUMAN SERVICES, DEPARTMENT OFNATIONAL INSTITUTES OF HEALTHNATIONAL INSTITUTES OF HEALTH NIAROCKVILLE, MD, 20852, USA

NAICS

Testing Laboratories and Services (541380)

PSC

MEDICAL- LABORATORY TESTING (Q301)

Original Source

https://sam.gov/opp/b2897664ab724bb6a441dbf8a2a81946/view
Timeline
    Description

    The Department of Health and Human Services, National Institutes of Health seeks proposals for a firm fixed-price contract for commercial services related to proteomics and mRNA sequencing analysis. The 6-month project focuses on detecting global proteins and mRNA in postnatal heart tissue samples from a specific mouse strain.

    The agency requires assistance in analyzing protein expression and mRNA signals to better understand their roles in cardiac cell survival and regeneration. Offerors should possess expertise in immunoprecipitation and mass spectrometry methods for a timely delivery of comprehensive analysis.

    This is a combined synopsis and solicitation for commercial services, incorporating FAR and HHSAR clauses on topics such as telecommunications equipment, equal employment opportunities, and system awards. Offerors must provide certifications and representations regarding telecommunications equipment, labor standards, and commercial product offerings.

    The contract, anticipated to be awarded based on technical merit and price, requires a response by 4:00 p.m. on August 23, 2024, to Procuring Contract Officer Eric McKay.

    Point(s) of Contact
    ERIC MCKAY
    (301) 480-2406
    eric.mckay@nih.gov
    Files
    Title
    Posted
    Attachment - 1 Statement of Work.pdf
    The government agency seeks a contractor to assist in a 6-month research project aimed at detecting global proteins and mRNA in a specific mouse strain. The purpose is to analyze protein expression and mRNA signals to understand their roles in heart cell survival and renewal. The agency will provide the necessary mouse tissue samples, and the contractor is tasked with developing methods for immunoprecipitation and mass spectrometry analysis. They must deliver comprehensive global proteomics and mRNA sequencing analysis, providing quantitative and qualitative results within a 90-day window. The agency emphasizes data ownership and has no requirements for travel or key personnel.
    FAR 52.204-24 Nov 2021.pdf
    The file concerns a mandate from the John S. McCain National Defense Authorization Act, prohibiting the use of certain telecommunications equipment or services in government contracts. The provision explicitly defines these prohibited items, clarifies the procurement guidelines, and mandates representations and certifications from offerors. Companies bidding on the contract must provide detailed information on their telecommunications equipment and services, ensuring compliance with the new restrictions. This certification process aims to ensure that contractors do not inadvertently use or provide equipment or services that are banned under Section 889 of the Act.
    FAR 52.204-26 Oct 2020.pdf
    The file pertains to the procurement process's requirement for Offerors to provide a representation regarding their compliance with specific telecommunications equipment and services provisions. Offerors must declare that they neither supply 'covered telecommunications equipment or services' nor use them in their operations. This representation is crucial, ensuring that contractors adhere to federal guidelines on the matter. The representation is binding and requires authorization from a responsible individual within the organization.
    FAR 52.212-5 (May 2024).pdf
    The file outlines mandatory clauses that must be included in contracts for commercial products and services procured by the government. It encapsulates a comprehensive range of legal requirements, encompassing topics such as whistleblower protections, ethical standards, labor laws, and procurement procedures. These clauses aim to ensure compliance with statutory and executive mandates, spanning from cybersecurity restrictions to small business subcontracting plans. Notably, it grants the Comptroller General access for examination of pertinent contractor records. The file also specifies which clauses subcontractors must follow, emphasizing the flow-down of essential terms while allowing some flexibility for commercial subcontracts. Overall, it serves as a compendium of legal obligations integral to the procurement process for commercial goods and services, ensuring compliance, transparency, and fairness in government contracting.
    FAR 52.222-52 (May 2014).pdf
    The file contains an exemption certification, mandated by the Service Contract Labor Standards statute, that certain service contracts are exempt from labor regulations. To qualify for the exemption, offerors must certify that their services meet specific criteria: they are sold regularly to non-governmental entities and the general public, priced according to established rates, performed by employees who only spend a small portion of their time on government work, and offered under consistent compensation plans. If an offeror certifies these conditions and the Contracting Officer verifies the exemption, the contract is exempt from labor regulations. However, failure to certify or meet the conditions leads to the inclusion of a labor standards clause in the contract, enforcing regulations on the offeror. This certification is a crucial step in the procurement process, as it determines the labor regulations applicable to the contract and potential exemptions.
    Invoicing Instructions With IPP 3-23.pdf
    This file outlines the updated invoice and payment provisions for government contracts, emphasizing timely payments and contractor responsibilities. Contractors must submit detailed invoices adhering to specific requirements, including unique identification numbers and tax information. Invoices should reflect the supplies delivered and services rendered, with shipping costs reimbursed only if authorized. Payments are due within 30 days of a proper invoice's receipt or government acceptance of the work, and interest penalties are applicable if payments are delayed. To benefit small businesses, contractors must accelerate payments to their subcontractors within 15 days of receiving government payments. Additionally, contractors are encouraged to submit payment requests electronically using the Invoice Processing Platform (IPP), although exceptions can be authorized. These provisions ensure efficient processing and prompt payment while providing clarity on invoice contents and submission methods.
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