The Technical Support and Operational Analysis (TSOA) Defense-in-Depth Experiment (DiDEX) 25 is initiated by the U.S. Army's Combat Capabilities Development Command to enhance counter-small Unmanned Aircraft Systems (C-sUAS) and other small unmanned systems (UxS) in urban environments. This Request for Information (RFI) seeks innovative technology contributions from industry, academia, and laboratories to improve warfighter capabilities in detecting, identifying, tracking, and neutralizing sUxS and UxS threats. The TSOA DiDEX 25 aims to address operational security and force protection challenges while fostering collaboration between military personnel and technology developers. The event, scheduled for Q1 FY26 in Austin, TX, will include field experiments to evaluate emerging technologies' effectiveness in dense urban settings. Respondents are invited to submit white papers and accompanying documents like Scout Cards, Quad Charts, and Planning Input Forms by the deadline of June 20, 2025. The initiative emphasizes the integration of sensor data, artificial intelligence for decision-making, and electronic warfare strategies to bolster military readiness against drone warfare challenges. Notably, proprietary information protection is guaranteed, and participation in the event does not imply any contract award. This initiative underlines the government's commitment to enhancing military capabilities through innovative technological solutions.