AMPHORA Microorganisms
ID: NB644010-25-00792Type: Sources Sought
Overview

Buyer

COMMERCE, DEPARTMENT OFNATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGYDEPT OF COMMERCE NISTGAITHERSBURG, MD, 20899, USA

NAICS

Research and Development in Biotechnology (except Nanobiotechnology) (541714)

Original Source

https://sam.gov/opp/625d24fe481d449e8013fb10f669e59b/view
Timeline
    Description

    The Department of Commerce, specifically the National Institute of Standards and Technology (NIST), is seeking sources for viable microorganisms to support the DARPA AMPHORA program, which focuses on microbial preservation in challenging environments. Contractors are required to provide contrived samples of specified microorganisms, including bacteria, fungi, and viruses, ensuring that the strains are of U.S. origin for specific pathogens and that necessary distribution rights are granted to third-party teams involved in the program. This initiative underscores the government's commitment to advancing biotechnology research while adhering to regulatory standards, particularly compliance with USDA regulations for animal and plant pathogens. Interested parties should contact Sadaf Afkhami at Sadaf.Afkhami@nist.gov or 301-975-3976 to discuss their capabilities and submit their responses, as NIST plans to analyze submissions and may conduct a competitive procurement by FY2025.

    Point(s) of Contact
    Sadaf Afkhami
    (301) 975-3976
    Sadaf.Afkhami@nist.gov
    Files
    Title
    Posted
    Sources Sought DARPA AMPHORA Strains (002).pdf
    The National Institute of Standards and Technology (NIST) issued a Sources Sought Notice regarding the provision of viable microorganisms for the DARPA AMPHORA program, which focuses on microbial preservation in challenging environments. NIST seeks to validate and verify methods by supplying contrived samples of specified microorganisms including bacteria, fungi, and viruses. Contractors are invited to demonstrate their capabilities to provide the needed microbial strains, which must be of U.S. origin for specific pathogens, and grant necessary rights for distribution to third-party teams within the AMPHORA program. Responses should detail the contractor's ability to supply microorganisms, proposed terms, availability timelines, and confirm compliance with USDA regulations for animal and plant pathogens. Additionally, interested parties are asked to provide background information about their organization, including certifications, past experiences, and relevant contracts. NIST plans to analyze responses and potentially conduct a competitive procurement by FY2025. This initiative highlights the government's focus on advancing biotechnology research while ensuring compliance with regulatory standards.
    Lifecycle
    Title
    Type
    AMPHORA Microorganisms
    Currently viewing
    Sources Sought
    Similar Opportunities
    SOURCES SOUGHT: AMPHORA Microorganisms
    Buyer not available
    The Department of Commerce, through the National Institute of Standards and Technology (NIST), is seeking sources for viable microorganisms to support the DARPA AMPHORA program's Independent Validation and Verification (IV&V) process. The procurement specifically requires various bacteria, fungi, and viruses, with a stipulation that any animal or plant pathogens must originate from the United States, and contractors must allow NIST to distribute these microorganisms to third-party teams involved in the program. This initiative is crucial for ensuring the integrity and reliability of the AMPHORA program's research and development efforts in biotechnology. Interested businesses are encouraged to respond with their capabilities, including business size classifications and relevant certifications, by submitting their information in a specified format, with a Request for Quotation expected in FY2025. For further inquiries, potential respondents can contact Sadaf Afkhami at Sadaf.Afkhami@nist.gov or by phone at 301-975-3976.
    Lyophilized and Fixed Mammalian Cells for Cell Counting
    Buyer not available
    The Department of Commerce, specifically the National Institute of Standards and Technology (NIST), is seeking sources for the procurement of lyophilized and fixed mammalian cells intended for cell counting applications. This opportunity aims to acquire biological products that are crucial for various research and development activities within the institute, emphasizing the importance of accurate cell counting in biological and medical research. Interested vendors should note that the place of performance is in Gaithersburg, Maryland, and are encouraged to reach out to Don Graham at deg@NIST.GOV or by phone at 301-975-8567 for further inquiries regarding this sources sought notice.
    Protein Biologic Analyzer
    Buyer not available
    The Department of Commerce, specifically the National Institute of Standards and Technology (NIST), is seeking sources for a Protein Biologic Analyzer, as part of a Sources Sought notice. This procurement aims to identify potential suppliers capable of providing analytical laboratory instruments that are crucial for the evaluation and analysis of protein biologics. Such instruments play a vital role in various scientific and industrial applications, including pharmaceuticals and biotechnology, where precise measurement and analysis of biological materials are essential. Interested vendors can reach out to Jennifer Priebe at jennifer.priebe@nist.gov or call 301-975-8717 for further information regarding this opportunity.
    In Vitro Assessments of Antimicrobial Activity
    Buyer not available
    The National Institutes of Health (NIH), specifically the National Institute of Allergy and Infectious Diseases (NIAID), is seeking proposals for the In Vitro Assessments of Antimicrobial Activity (IVAAA) program through solicitation RFP 75N93024R00024. This initiative aims to support in vitro testing to evaluate the therapeutic potential of compounds against over 270 infectious agents, facilitating the development of vaccines, therapeutics, and diagnostics for infectious diseases. The program is critical for enhancing public health preparedness and response capabilities, particularly in addressing emerging health threats such as bioterrorism and infectious diseases. Proposals are due by March 10, 2025, with a funding range of $2,500 to $15 million available through January 14, 2033. Interested parties can direct inquiries to Alexander Beraud at alexander.beraud@nih.gov or Brian Madgey at brian.madgey@nih.gov.
    Monoclonal Antibody Reference Material Vialing
    Buyer not available
    The National Institute of Standards and Technology (NIST) is seeking information from qualified sources for the vailing of monoclonal antibody reference materials as part of its Biomanufacturing Initiative. The procurement aims to identify capabilities for diluting bulk biopharmaceutical formulations under aseptic conditions, aliquoting them into specified units, and ensuring compatibility with cryogenic storage, while maintaining purity standards. This initiative is crucial for providing reliable reference materials that support the biopharmaceutical industry in developing and characterizing monoclonal antibody drugs. Interested parties should submit their capabilities and relevant experience to Don Graham at deg@nist.gov by the specified response date, with the expectation of a Request for Quotation being issued within 120 days.
    CDC DFWED NARST Sensititre Supplies
    Buyer not available
    The Centers for Disease Control and Prevention (CDC) is seeking to award a sole source contract for antimicrobial resistance testing supplies, specifically Sensititre™ broth microdilution testing products, from ThermoFisher Scientific. This procurement is essential for the National Antimicrobial Resistance Monitoring System (NARMS), which has utilized these proprietary materials since 1996 to ensure a standardized approach to monitoring enteric bacteria resistance. The unique nature of these supplies necessitates this sole source approach, as alternatives would require significant investments in new equipment and validation processes, potentially disrupting critical surveillance efforts. Interested parties may respond within 15 days to express their interest, with proposals directed to contract specialist Ashley Williams at dal3@cdc.gov.
    2026 NIAID DMID Omnibus Broad Agency Announcement
    Buyer not available
    The Department of Health and Human Services, through the National Institute of Allergy and Infectious Diseases (NIAID), is soliciting proposals for the 2026 DMID Omnibus Broad Agency Announcement (BAA) aimed at advancing research and development of medical countermeasures against antimicrobial-resistant pathogens and viruses with pandemic potential. The BAA encompasses two primary research areas: Research Area 001 focuses on developing therapeutics, vaccines, and diagnostics for antimicrobial-resistant bacterial and fungal pathogens, while Research Area 002 targets the creation of Direct Acting Antivirals for viruses of pandemic potential. This initiative is critical for addressing public health challenges related to infectious diseases, with an estimated funding of $28.5 million available for awards in fiscal year 2026. Proposals for Research Area 001 are due by February 21, 2025, and for Research Area 002 by January 21, 2025; interested parties can contact Swee L. Teo at teosl@niaid.nih.gov or Brian Madgey at brian.madgey@nih.gov for further information.
    Sources Sought Notice for Extreme Thermal Cycling Chamber
    Buyer not available
    The Department of Commerce, specifically the National Institute of Standards and Technology (NIST), is conducting market research through a Sources Sought Notice for an Extreme Thermal Cycling Chamber. This procurement aims to identify potential sources capable of providing a chamber that meets specific requirements for accelerated aging experiments, which are crucial for studying the long-term reliability of materials used in advanced semiconductor packaging. The chamber must accommodate various sample types, including films and wafers, and provide a wide temperature range with rapid thermal cycling capabilities, essential for supporting the CHIPS Metrology program. Interested vendors should submit their responses, including technical specifications and company information, to the primary contact, Nina Lin, at nina.lin@nist.gov, by the specified deadline, ensuring they are registered and active in SAM.gov.
    NIAID Virology Quality Assurance
    Buyer not available
    The National Institute of Allergy and Infectious Diseases (NIAID) is soliciting proposals for the Virology Quality Assurance (VQA) program under RFP number 75N93024R00030, aimed at providing comprehensive quality assessment for virologic testing related to HIV and other viral pathogens in clinical trials. The program's objectives include ensuring the validity of laboratory data through proficiency testing, real-time assay validation, and the development of performance standards, while also addressing public health emergencies and increasing laboratory demands. This initiative is crucial for maintaining high-quality laboratory practices and supporting ongoing research in virology. Proposals are due by April 8, 2025, and interested parties should direct inquiries to the primary contact, Shawnice Williams, at shawnice.williams@nih.gov or 301-761-5431.
    Scientific, Technical Research and Program Management Support Services for USAMRIID
    Buyer not available
    The Department of Defense, through the Defense Health Agency (DHA), is seeking qualified contractors to provide scientific and technical research and program management support services for the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID). The procurement aims to enhance research capabilities in biotechnology, specifically focusing on health-related research and development services. This opportunity is critical for advancing the U.S. military's medical research efforts, particularly in the field of infectious diseases. Interested parties should note that this is an 8(a) set-aside opportunity, and they can reach out to Christina Lewis at christina.m.lewis14.civ@health.mil or Jayme Fletcher at jayme.l.fletcher2.civ@health.mil for further information.