The Department of Health and Human Services, specifically the National Institutes of Health (NIH) through the National Heart, Lung, and Blood Institute (NHLBI), intends to negotiate a contract modification with Illumina, Inc. for the supply of proprietary reagents and consumables essential for the operation of Illumina sequencing and genotyping systems utilized by the NIH Intramural Sequencing Center (NISC). This modification is critical to ensure the continuous availability of high-quality, brand-name supplies necessary for ongoing genomic research projects, which play a vital role in diagnosing diseases and developing new therapies. The contract extension will prolong the period of performance from September 3, 2020, to March 2, 2026, and while interested parties may express their capabilities, this is not a solicitation for proposals, as the government retains the right to pursue competitive options if necessary. For further inquiries, interested parties can contact Ethan J. Mueller at ethan.mueller@nih.gov or Dorothy L. Maxwell at dorothy.maxwell@nih.gov.