The Department of Health and Human Services, specifically the National Institutes of Health (NIH), is seeking qualified small businesses to provide an Opera Phenix Plus High-Content Screening System or an equivalent product for the Intramural Center for Alzheimer’s and Related Dementias (CARD). The procurement aims to acquire a high-content imaging system capable of analyzing cellular samples, including organoids and tissue slices, to support research on neurodegenerative diseases. This initiative is critical for advancing the understanding of Alzheimer’s disease and related conditions through the analysis of induced pluripotent stem cells (iPSCs). Interested vendors must submit their capability statements by December 27, 2024, at 5 PM Eastern Time, to Iris Merscher at iris.merscher@nih.gov, ensuring compliance with the specified requirements and guidelines.