Small Business Sources Sought: Amplifiers and digitizers for use in electrophysiology experiments
ID: 75N95024Q00468Type: Sources Sought
Overview

Buyer

HEALTH AND HUMAN SERVICES, DEPARTMENT OFNATIONAL INSTITUTES OF HEALTHNATIONAL INSTITUTES OF HEALTH NIDABethesda, MD, 20892, USA

NAICS

Analytical Laboratory Instrument Manufacturing (334516)

PSC

LABORATORY EQUIPMENT AND SUPPLIES (6640)

Set Aside

Total Small Business Set-Aside (FAR 19.5) (SBA)

Original Source

https://sam.gov/opp/df7d3a86a1044c5a890b479171508bfe/view
Timeline
    Description

    Sources Sought: Amplifiers and digitizers for use in electrophysiology experiments

    The Department of Health and Human Services, Department of, National Institutes of Health, National Institutes of Health NIDA, has issued a Sources Sought notice for the procurement of amplifiers and digitizers. These equipment will be used in electrophysiology experiments to examine the cellular excitability of neurons located in the midbrain dopamine system and basal ganglia.

    The purpose of this requirement is to acquire the necessary equipment to support research in the Cellular Neurophysiology Section (CNS) focused on the circuit and cellular properties of neurons. Specifically, the CNS is interested in understanding how synaptic and intrinsic conductances expressed on dopamine neurons differ among subpopulations, particularly calcium permeable conductances such as voltage-gated calcium channels and glutamate-activated receptors. This research aims to provide insight into why dopamine neurons in the substantia nigra pars compacta (SNc) are particularly vulnerable in Parkinson's disease.

    The project requires two amplifiers and two digitizers that meet specific requirements. The amplifiers must have features such as external trigger command, automatic mode-switching between current and voltage-clamp, and the ability to detect and protect the cell from damage. The digitizers must be compatible with pClamp software, sample at 500 kHz per channel, and have a humsilencer to eliminate line-frequency noise.

    The contractor will be responsible for delivering and installing the equipment within six months after receipt of the order. A warranty period of twelve months from the date of installation, inspection, and acceptance is required.

    Interested companies should submit a capability statement addressing each project requirement, including the total number of employees, professional qualifications of personnel, and any relevant government-wide acquisition contracts. The response must include the company's name, Unique Entity ID from SAM.gov, physical address, and point of contact information.

    Responses must be submitted electronically to the Contracting Officer by July 30, 2024, 5 pm Eastern Time. The Government reserves the right to use the information provided for any necessary purposes and may publish a presolicitation synopsis and solicitation in www.sam.gov.

    Please ensure your response is complete and sufficiently detailed to demonstrate your qualifications for the work.

    Point(s) of Contact
    FEELY, EVAN C
    13018275301
    evan.feely@nih.gov
    Files
    No associated files provided.
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