The National Aeronautics and Space Administration (NASA) is preparing to issue a Research Announcement (NRA) titled "Human Exploration Research Opportunities (HERO) - 2025," aimed at soliciting applied research to support NASA's Human Research Program (HRP). The research will focus on five key elements: Space Radiation, Human Health Countermeasures, Exploration Medical Capability, Human Factors and Behavioral Performance, and Research Operations and Integration. This initiative is crucial for advancing human exploration in space, with anticipated awards ranging from $250,000 for one-year projects to $1.5 million for multi-year projects, depending on specific appendices released throughout the solicitation period. Interested parties should monitor the NASA Solicitation and Proposal Integrated Review and Evaluation System (NSPIRES) for updates, with the NRA expected to be released around November 1, 2024, and proposals due within the following year. For inquiries, contact Tracy L. Quintanilla at Tracy.L.Quintanilla@nasa.gov.