The Department of Health and Human Services, specifically the National Institutes of Health, is seeking proposals for the Miniaturization and Automation of Tissue Chip Systems (MATChS) through their SBIR program. The goal of this funding opportunity is to support the development of benchtop, portable, automated systems that maintain 3D tissue constructs and provide biologically relevant outputs of tissue health and function. The technology should be easy to use, have integrated in-line sensors, and be capable of rapid and reproducible high-throughput analysis. The system should also be capable of maintaining culture without external intervention and be remotely monitored through real-time biosensing. The fabrication procedure must be cost-effective, mass producible, and robust. The funding opportunity is open for Phase I, Phase II, Fast-Track, and Direct to Phase II grant applications. The project duration is from 2024 to 2026, with multiple application due dates. More details can be found on the grants.gov website.