The Department of Defense (DoD), specifically the Army, is seeking proposals for the Small Business Innovation Research (SBIR) program focused on the metagenomic discovery of biosensors for water contaminants of concern. The primary objective is to develop a metagenomic screening approach to identify novel biosensors capable of detecting harmful water contaminants, particularly those relevant to military operations, such as per- and polyfluoroalkyl substances (PFAS), toxins, and uranium. This initiative is crucial for ensuring clean drinking water, especially in resource-limited environments, and has significant implications for both military and civilian water quality management. Phase I proposals are invited with a funding limit of $250,000 for a six-month performance period, with submissions due by September 24, 2025. For more information, interested parties can visit the solicitation link at https://www.dodsbirsttr.mil/topics-app/.