The Department of Health and Human Services, specifically the National Institutes of Health, is seeking proposals for the NIA Research and Entrepreneurial Development Immersion (REDI): Entrepreneurial Small Business Transition Award (R43/R44 Clinical Trial Optional). This initiative aims to support the development and commercialization of academic technologies by providing funding for small business research and development activities. The focus is on facilitating the transition and experiential entrepreneurial career development of early-career scientists, while also addressing significant unmet needs in the field of aging research. The program encourages the hiring and salaries of early-stage researchers as Program Directors/Principal Investigators (PDs/PIs) in small business concerns (SBCs). The PDs/PIs are expected to bring extensive research knowledge and experience to the SBCs, while also receiving robust entrepreneurial training and mentorship. The program emphasizes the importance of mentorship and entrepreneurship training, with applicants required to identify at least one mentor and submit a career development plan that includes coursework and workshops. Eligibility is limited to early-career scientists, including late-stage graduate students and postdoctoral fellows. The proposed scientific projects must align with the mission of the National Institute on Aging (NIA) and fall within the scope of the traditional SBIR/STTR grant mechanisms. The program encourages collaboration with existing NIH and federal resources and programs, as well as leveraging entrepreneurial training activities from both federal and private-sector partners. The application process allows for both Phase I and Fast-track applications. The deadline for submission is October 26, 2023. For more information, interested parties can visit the solicitation agency URL: link.