The National Institutes of Health (NIH) and The Centers for Disease Control and Prevention (CDC) are seeking proposals for small business innovation research (SBIR) contract proposals. The specific topic of the solicitation is "Small Manufacturing Systems to Produce Research Grade Pharmaceutical Intermediates". The goal of this initiative is to develop compact tools and devices capable of manufacturing key chemical intermediates at the benchtop, allowing for just-in-time delivery of materials to optimize research operations. The devices should be able to speed up the preclinical drug development stage by providing on-demand access to intermediates that can be rapidly diversified or scaled up for animal studies. The project aims to leverage automation in synthetic chemistry to shift the way common intermediates in medicinal chemistry are acquired in the laboratory. The budget for Phase I is $325,000 for 9 months, and for Phase II is $2,000,000 for 2 years. The solicitation is open until November 14, 2023. For more information, visit the SBIR topic link or the solicitation agency URL.