The Department of Health and Human Services, specifically the National Institutes of Health, is seeking proposals for the development of Interactive Digital Media (IDM) Biomedical Science Resources for Pre-College Students and Teachers through the SBIR program. IDM refers to digital computer-based systems that respond to user actions by presenting content such as text, images, animations, audios, videos, and video games. These resources have been widely used in STEM education to enhance learning experiences. The goal of this solicitation is to develop innovative IDM products that engage users in interactive learning experiences, disseminate knowledge of biomedical science, enhance student interest in the subject, and strengthen problem-solving skills. The products should also focus on developing students' quantitative and computational skills. They can be designed for use inside or outside the classroom, for individual or group settings, with or without teacher or adult participation. Real-time student assessment features are strongly encouraged. The products should be age, grade, and culturally appropriate for the target audience and developed on accessible IDM platforms. The solicitation is open for proposals until September 6, 2025, and more details can be found on the grants.gov and NIH websites.