Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Therapeutic Agent Characterization and Preclinical Efficacy Studies
Grant Opportunity Analysis
The National Institutes of Health (NIH) is offering the Innovation Grants to Nurture Initial Translational Efforts (IGNITE) program, aimed at supporting pharmacodynamic, pharmacokinetic, and efficacy studies for therapeutic agents targeting neurological disorders and non-opioid analgesics with minimal addiction liability. This initiative seeks to demonstrate the biological activity of proposed therapeutic agents, which may include small molecules or biologics, through validated in vivo models or New Approach Methodologies (NAMs). While applications are not currently being solicited, this notice allows potential applicants to prepare meaningful collaborations and projects ahead of the anticipated application period. Interested parties can reach out via email at NINDS_IGNITE@nih.gov for further information, with the estimated synopsis post date set for July 30, 2026, and the estimated award date projected for July 1, 2027.
Eligible Applicants
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).