CRO Services for Single-Cell Multiomics Profiling

NIDA, on behalf of NCATS, issued a Sources Sought Notice (Solicitation Number: 75N95025Q00238) for Human Discovery Panel (HDP) analysis services. The purpose is to gather information on qualified small businesses capable of performing single-cell multiomic data analysis to inform NCATS on transcriptomic and proteomic alterations during inflammatory sensitization in human pluripotent stem cell-derived sensory neurons (hPSC-SNs). The selected contractor will analyze 33 samples, providing single-cell RNA sequencing and DNA barcoded antibody analysis targeting up to 325 distinct proteins. Interested vendors must submit capability statements by August 12, 2025, detailing their technical abilities, personnel qualifications, company information (including NAICS 541380), and any relevant government contracts. This notice is for information gathering only and does not constitute a solicitation for proposals.

The National Center for Advancing Translational Sciences (NCATS) intends to award a sole-source contract to Proteintech Group, Inc. for "CRO Services for Single-Cell Multiomics Profiling." This non-competitive procurement, classified under NAICS code 541714 (Research and Development in Biotechnology), is authorized by FAR Part 13 for simplified acquisitions. NCATS requires a contract research organization (CRO) to perform Human Discovery Panel (HDP) analysis on 33 hPSC-SN samples under inflammatory conditions, providing single-cell multiomic data. Proteintech Group, Inc. was selected because its HDP platform is deemed the only one capable of combining single-cell RNA sequencing with DNA barcoded antibodies targeting up to 325 distinct proteins specific to the required samples. This notice is not a request for competitive proposals, but interested parties may submit capability statements to challenge the sole-source determination.