The Centers for Disease Control and Prevention (CDC) is offering a cooperative agreement to enhance the capacity of public health staff in Central America under the President's Emergency Plan for AIDS Relief (PEPFAR). The initiative aims to address gaps in achieving the 95-95-95 targets to end the AIDS epidemic by integrating HIV services into broader health systems, scaling up access to life-saving services, and improving treatment initiation and retention for high-risk populations. This funding opportunity is critical for strengthening healthcare delivery and ensuring sustainable epidemic control in El Salvador, Guatemala, Honduras, Nicaragua, and Panama, with an estimated total funding of $20 million for the first year. Interested applicants can reach out to the grantor at pepfarfoas@cdc.gov, with applications due by February 17, 2026, and awards expected to be announced by September 30, 2026.