The National Institutes of Health (NIH) is offering the George M. O’Brien Urology Cooperative Research Centers Program (U54 Clinical Trial Optional), aimed at fostering impactful, multi-disciplinary research in urology through diverse collaborations. This program seeks to continue the support for the NIDDK George M. O’Brien Urology Cooperative Research Centers, which serve as a national resource for the urology research community. With an estimated total program funding of $5.3 million and the expectation of awarding five grants, interested applicants, including Indian/Native American Tribal Governments, eligible federal agencies, and non-domestic entities, should note that the application period will open with a synopsis posted on April 1, 2026, and close on July 1, 2026. For further inquiries, applicants can contact Deepak Nihalani at deepak.nihalani@nih.gov or by phone at 301.594.6417.