The National Institutes of Health (NIH) is set to renew the Notice of Funding Opportunity (NOFO) for the Multiple Chronic Disease Research Centers, aimed at enhancing research on the prevention, diagnosis, treatment, and management of multiple chronic diseases (MCDs). This initiative will support both existing and new regional comprehensive research centers that focus on innovative strategies and interventions to improve health outcomes, particularly among populations facing health disparities. With an estimated total program funding of $55 million and the expectation of awarding 11 grants, potential applicants are encouraged to begin forming collaborations and developing projects, as applications are not currently being solicited. For further inquiries, interested parties may contact Dr. Dolly Penn at dolly.penn@nih.gov or by phone at 301-496-8676, with key deadlines including an estimated synopsis post date of May 16, 2025, and a close date of July 25, 2025.