The Centers for Disease Control and Prevention (CDC) is offering a cooperative agreement to implement and sustain a comprehensive response to HIV and provide technical assistance to strengthen the capacity of regional authorities in the United Republic of Tanzania under the PEPFAR initiative. The primary objectives include improving the quality of life for individuals living with HIV and achieving the UNAIDS 95-95-95 targets through enhanced service delivery models, health system strengthening, and capacity-building for local and regional government agencies. This funding opportunity, with an anticipated total of $35 million for the first fiscal year, is open to unrestricted applicants, and interested parties should note that applications must be submitted electronically by 11:59 PM ET on February 17, 2026, with awards expected to be announced by September 30, 2026. For further inquiries, applicants can contact the grantor at pepfarfoas@cdc.gov.