Single Source: HeartShare 2.0: Refining Heart Failure Subtypes and Treatment Targets for Personalized Clinical Trials - Data Translation Center (U54 Clinical Trial Optional)
Grant Opportunity Analysis
The National Heart, Lung, and Blood Institute within the National Institutes of Health is seeking a single-source cooperative agreement for Northwestern University to renew the HeartShare Data Translation Center and advance the HeartShare 2.0 program focused on refining heart failure subtypes and treatment targets for personalized clinical trials. The work centers on coordinating the overall project, overseeing enrollment of a cohort of patients with heart failure with preserved ejection fraction, curating and analyzing prospective deep phenotyping data, and supporting planning, implementation, and analysis for clinical trials. This is a non-competitive opportunity limited to Northwestern University, with peer-reviewed applications considered only if meritorious, and the project is expected to connect with existing HeartShare 1.0 components and the AMP HF partnership. The close date is July 9, 2026, and the opportunity summary lists up to $2,541,000 in total costs for FY2027 with a maximum project period of six years.
Eligible Applicants
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibilityThis is a non-competitive funding opportunity intended, if the peer-reviewed application is meritorious, to fund a single award. Only the following applicant is eligible to apply for this single source funding: Northwestern University.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.