DoD Peer Reviewed Medical Research Program, Clinical Trial Award

The Department of Defense (DOD) has issued a Program Announcement for the Peer Reviewed Medical Research Program (PRMRP) Clinical Trial Award (Funding Opportunity Number: HT942525PRMRPCTA) for fiscal year 2025. This initiative focuses on the rapid implementation of clinical trials that significantly impact disease treatment and management relevant to military health. Approximately $32 million is allocated for about four awards, each capped at $8 million, with applications due by July 21, 2025. Eligible applicants include various organizations, both domestic and foreign, public and private. The application process consists of a two-step approach, requiring a pre-application followed by a full application. The program prioritizes clinical trials over animal studies, mandating that preclinical work must be completed prior to the award start date. Key topic areas include autoimmune disorders, cardiovascular health, infectious diseases, neuroscience, and more, each with specific strategic goals that applicants must address. The program aims to enhance military health by promoting significant research advancements, encouraging collaboration between academia, government, and industry to address the military's unique health needs. Regulatory agency approvals are essential for interventions, emphasizing rigorous safety and ethical standards.