The Centers for Disease Control and Prevention (CDC) is offering a cooperative agreement to strengthen Botswana's national data, performance management, and health security systems as part of the President's Emergency Plan for AIDS Relief (PEPFAR). The initiative aims to provide targeted technical assistance to the Government of Botswana (GoB) to enhance health security and data management capabilities, ensuring effective HIV-related strategic information and health security programs at various administrative levels. This funding opportunity, with an estimated total of $4 million for the first fiscal year, is open to unrestricted applicants, and interested parties should submit their applications electronically by February 17, 2026, to be considered for awards expected to be announced by September 30, 2026. For further inquiries, applicants can contact the grantor at pepfarfoas@cdc.gov.