The Centers for Disease Control and Prevention (CDC) is offering a cooperative agreement to establish a nationwide longitudinal cohort of repeat blood donors aimed at estimating the burden of respiratory viruses and assessing immunologic responses. The project will involve monitoring changes in antibody titers against various respiratory viruses, surveying donors for risk factors, and creating a repository for future analysis as new assays are developed. This initiative builds on previous national serosurveillance studies conducted during the COVID-19 pandemic and seeks to adapt those methodologies to evaluate the national burden of SARS-CoV-2 and other respiratory viruses. Interested applicants can apply for funding ranging from $3 million to $4.5 million, with a total program funding of $26.5 million available, and must submit their applications by February 16, 2024. For further inquiries, contact Dr. Jamal Bankhead at JBankhead@cdc.gov.