Complex Integrated Multi-Component Projects in Aging Research (U19 Clinical Trial Optional)
ID: 360911Type: Posted
Overview

Buyer

National Institutes of Health (HHS-NIH11)

Eligible Applicants

Others

Funding Category

Health

Funding Instrument

Cooperative Agreement

Opportunity Category

Discretionary

Cost Sharing or Matching Requirement

Yes
Timeline
    Description

    The National Institutes of Health (NIH) is inviting applications for the Complex Integrated Multi-Component Projects in Aging Research (U19 Clinical Trial Optional) grant, aimed at supporting large-scale, multidisciplinary research projects focused on aging. This opportunity encourages the formation of collaborative teams that will propose integrated research programs addressing a common hypothesis related to aging, with an emphasis on coordination among various project components. While applications are not currently being solicited, potential applicants are encouraged to prepare meaningful collaborations and responsive projects in anticipation of the upcoming Notice of Funding Opportunity (NOFO), with an estimated synopsis posting date of March 25, 2026, and a closing date of May 25, 2026. For further inquiries, interested parties can contact the NIA Scientific Contact at nia_scicontact@mail.nih.gov.

    Point(s) of Contact
    NIA Scientific Contact
    N/A
    nia_scicontact@mail.nih.gov
    Files
    No associated files provided.
    Similar Opportunities
    Notice of Intent to Publish a Funding Opportunity Announcement for Facilitating Preclinical and Early Phase Human Studies for New Therapeutics (UG3/UH3 Clinical Trial Optional)
    National Institutes of Health
    The National Institutes of Health (NIH) plans to publish a Notice of Funding Opportunity (NOFO) for facilitating preclinical and early phase human studies for new therapeutics, specifically targeting aging-related conditions. This initiative aims to advance T1 translational aging research, focusing on therapeutics that progress from preclinical stages to first-in-human trials, addressing conditions such as sarcopenia and heart failure with preserved ejection fraction (HFpEF). The funding opportunity, categorized under health-related activities, will utilize the UG3/UH3 Cooperative Agreement mechanism, with an estimated total program funding of $2.5 million. Interested applicants should prepare to submit their applications by fall 2024, with the NOFO expected to be published in summer 2024 and awards anticipated by July 2025.
    Novel Approaches to Advance Precision Aging and Cognitive Health
    National Institutes of Health
    The National Institutes of Health (NIH) is preparing to publish a Notice of Funding Opportunity (NOFO) titled "Novel Approaches to Advance Precision Aging and Cognitive Health," aimed at soliciting applications that leverage innovative study designs and methods, including machine learning and artificial intelligence, to enhance cognitive health in older adults. This initiative seeks to develop personalized prevention plans and interventions by discovering health and function profiles at the individual level, encompassing research from cellular to societal levels. The grant will utilize the R01 activity code, with applications not currently being solicited; however, potential applicants are encouraged to begin forming collaborations and project ideas in anticipation of the funding opportunity. For further inquiries, interested parties may contact Dr. Molly Wagster at wagsterm@nia.nih.gov or by phone at 301-496-9350. The estimated synopsis post date is August 6, 2026, with a close date of October 6, 2026, and an anticipated award date of July 6, 2027.
    Renewal of the Clinician-Scientists Transdisciplinary Aging Research (Clin-STAR) Coordinating Center
    National Institutes of Health
    The National Institutes of Health (NIH) is preparing to release a Notice of Funding Opportunity (NOFO) for the renewal of the Clinician-Scientists Transdisciplinary Aging Research Coordinating Center (Clin-STAR CC), aimed at enhancing aging research across various clinical disciplines. This initiative seeks to support clinician-investigators by providing a national resource that fosters collaboration, mentorship, and interdisciplinary research projects focused on aging, ultimately improving patient-centered care for older adults. The funding will also prioritize geographic representation and diversity among early career clinician-scientists in aging research. While applications are not currently being solicited, interested parties can prepare for the opportunity, with the estimated synopsis posting date on August 17, 2025, and a projected award date of July 17, 2026. For further inquiries, contact Alexis Bakos, Ph.D., MPH, RN at alexis.bakos@nih.gov or call 301-480-8538.
    Renewal of NIA Research Centers Collaborative Network (RCCN)
    National Institutes of Health
    The National Institutes of Health (NIH) is set to publish a Notice of Funding Opportunity (NOFO) for the renewal of the Research Centers Collaborative Network (RCCN), aimed at enhancing collaborations across its seven research centers focused on aging research. This initiative seeks to leverage NIH's significant investments by fostering interdisciplinary efforts and sustaining high-value activities, while also encouraging new initiatives such as pilot funding programs and enhanced mentoring infrastructure. Interested applicants, particularly those with expertise in aging research, are advised to prepare for this opportunity, with the estimated synopsis posting date on March 1, 2026, and a closing date for applications anticipated by May 25, 2026. For further inquiries, potential applicants can contact Amelia Karraker at amelia.karraker@nih.gov or by phone at 301-496-3131.
    NIA Multi-site Clinical Trial Implementation Grant (R01 Clinical Trial Required)
    National Institutes of Health
    The National Institutes of Health (NIH), through the National Institute on Aging (NIA), has announced the NIA Multi-site Clinical Trial Implementation Grant (R01 Clinical Trial Required) to support investigator-initiated multi-site interventional clinical trials focused on aging-related research. This funding opportunity aims to foster innovative biomedical and behavioral studies that address the complexities of aging, particularly in populations with multiple chronic conditions and polypharmacy. Eligible applicants include a diverse range of organizations such as higher education institutions, nonprofits, and tribal governments, with an emphasis on rigorous trial designs that ensure ethical considerations and participant diversity. Interested parties should note that the application deadline is January 7, 2026, and further details can be found at the provided NIH grants link, with inquiries directed to grantsinfo@nih.gov.
    Multidisciplinary Studies of HIV/AIDS and Aging (R01 Clinical Trial Optional)
    National Institutes of Health
    The National Institutes of Health (NIH) has announced a Notice of Funding Opportunity (NOFO) titled "Multidisciplinary Studies of HIV/AIDS and Aging," inviting applications for research that explores the intersection of HIV and aging. The primary objectives of this grant are to enhance understanding of the biological, clinical, and socio-behavioral aspects of aging in individuals living with HIV, as well as to improve strategies for testing, preventing, and treating HIV and managing related health complications. This funding opportunity is significant for advancing health interventions for older adults affected by HIV, with eligible applicants including a wide range of institutions such as higher education entities, community organizations, and tribal governments. Interested parties should note that the application deadline is May 7, 2027, and can find further details and guidance by contacting NIH Grants Information at grantsinfo@nih.gov or visiting the official announcement at https://grants.nih.gov/grants/guide/pa-files/PAR-24-091.html.
    Multidisciplinary Studies of HIV/AIDS and Aging (R21 Clinical Trial Optional)
    National Institutes of Health
    The National Institutes of Health (NIH) is offering a funding opportunity for multidisciplinary research on HIV/AIDS and aging through the R21 Exploratory/Developmental Research Grant program. This initiative invites applications that aim to enhance the understanding of the biological, clinical, and socio-behavioral aspects of aging in the context of HIV infection, with specific objectives to improve prevention, testing, treatment strategies, and management of HIV-related health issues in diverse populations, particularly older adults aged 70 and above. The grant provides funding of up to $275,000 for a two-year period, with key submission dates starting April 4, 2024, and a closing date for applications set for January 7, 2027. Interested applicants can find more information and guidelines at the NIH grants website or contact NIH Grants Information at grantsinfo@nih.gov for further inquiries.
    NIA Multi-site Clinical Trial Implementation Grant (R01 Clinical Trial Required)
    National Institutes of Health
    The National Institutes of Health (NIH), through the National Institute on Aging (NIA), has announced the NIA Multi-site Clinical Trial Implementation Grant (R01 Clinical Trial Required) to support the implementation of investigator-initiated multi-site interventional clinical trials focused on aging research. These trials must be hypothesis-driven and aim to address significant health challenges faced by populations aged 65 and older, particularly concerning multimorbidity and polypharmacy. This funding opportunity is crucial for advancing scientific understanding and improving health outcomes for older adults, with applications accepted for new, renewal, and resubmission proposals, and no budget limits as long as they align with project needs. Interested applicants can find more information and submit their proposals by January 7, 2026, and should direct inquiries to grantsinfo@nih.gov.
    Notice of Intent to Publish a Notice of Funding Opportunity for Centers on the Demography and Economics of Aging and Alzheimer�s Disease and Alzheimer�s Disease Related Dementias Coordinating Center (U24 Clinical Trial Optional)
    National Institutes of Health
    The National Institutes of Health (NIH) intends to publish a Notice of Funding Opportunity (NOFO) for the establishment of a Coordinating Center focused on the Demography and Economics of Aging, including Alzheimer’s Disease and Alzheimer’s Disease-Related Dementias (AD/ADRD). The objective of this cooperative agreement is to create a hub that facilitates collaboration among various D&E Centers, scholars, and the research community, enhancing the scientific impact and fostering synergies across related programs and infrastructures. This initiative is crucial for promoting an inclusive research environment and raising awareness about the demography and economics of aging. The estimated total program funding is $1,320,000, with an award ceiling of $800,000, and the application process is expected to open in July 2024, with submissions due by October 2024. Interested applicants should prepare to develop meaningful collaborations in advance of the application deadline.
    Notice of Intent to Publish a Funding Opportunity Announcement for Advancing Diversity in Aging Research (ADAR) through Undergraduate Education Coordinating Center (U24 Clinical Trial Not Allowed)
    National Institutes of Health
    The National Institutes of Health (NIH) is preparing to publish a Notice of Funding Opportunity (NOFO) aimed at advancing diversity in aging research through the establishment of a coordinating center under the Advancing Diversity in Aging Research (ADAR) initiative. This initiative seeks to develop and maintain a center that will support undergraduate education in aging research, with the NOFO expected to be a companion to the existing funding opportunity PAR-24-135. The anticipated funding amount for this cooperative agreement is $800,000, with one award expected to be made, and the application process is projected to open in May 2025, following a synopsis release in February 2025. Interested applicants should prepare to submit their proposals by the estimated closing date of May 25, 2025, with awards expected to be made by March 1, 2026.