Advancing Outbreak Detection, Notification, and Response Capacity by Implementing 7-1-7 in Partner Countries

This Notice of Funding Opportunity (NOFO), opportunity number CDC-RFA-JG-26-0214, is issued by the Centers for Disease Control and Prevention’s (CDC) Division of Global Health Protection. With an estimated Year 1 funding total of $25 million, this five-year cooperative agreement aims to award 5 to 10 recipients to strengthen partner countries' capacities to detect, notify, and respond to infectious disease outbreaks. The program utilizes the Detect-Notify-Respond (D-N-R) framework integrated with the time-bound "7-1-7" target approach: detecting suspected outbreaks within 7 days, notifying authorities within 1 day, and initiating an effective response within 7 days. These efforts are designed to contain biological threats locally, protect American interests, and foster long-term self-reliance in partner nations. The funding is structured across six components. Component 1 ($4 million ceiling per recipient) represents core annual priorities across multiple countries or regions, while Components 2 through 6 (ceilings ranging from $3 million to $8 million) are designed as "approved but unfunded" rapid response mechanisms for localized, regional, national, or emerging infectious disease emergencies. Eligible applicants include government entities, higher education institutions, nonprofits, for-profit organizations, small businesses, and foreign entities. Applications must cover all components and be submitted by August 14, 2026. Reviewers will evaluate proposals based on background and approach (35 points), evaluation and performance measurement (30 points), and organizational capacity (35 points), with a 10-point preference given to documented local in-country partners.

This Notice of Funding Opportunity (NOFO), number CDC-RFA-JG-26-0214, issued by the Centers for Disease Control and Prevention (CDC) Division of Global Health Protection, aims to strengthen partner countries' capacities to rapidly detect, notify, and respond to infectious disease outbreaks. Utilizing the time-bound Detect-Notify-Respond (D-N-R) and 7-1-7 target frameworks, the program seeks to detect outbreaks within 7 days, notify authorities within 1 day, and initiate an effective response within 7 days. With an expected Year 1 funding total of $25,000,000, the CDC anticipates making five to ten cooperative agreement awards for a five-year performance period. Applications are due by August 14, 2026. Eligible applicants include domestic and foreign government entities, higher education institutions, nonprofits, and commercial organizations. A 10-point funding preference is available for documented in-country local partners. The program utilizes a component funding strategy across six structured tiers: Component 1 covers core, multi-country priorities (up to $4,000,000), while Components 2 through 6 serve as approved-but-unfunded (ABU) rapid-response mechanisms for localized, regional, national, and emerging infectious disease threats of varying scales. Proposed projects must target bilateral or regional partner countries aligned with CDC's global health presence. Applications must include separate budgets, work plans, an Evaluation and Performance Measurement Plan (EPMP), and a Data Management Plan (DMP) for all components. Funded activities must strictly align with CDC values, gold-standard scientific practices, and federal spending regulations.