Controlled Clinical Trials on Long-Term Effects of Nutritional Interventions on the Progression of Risk Factors for Age-Related Chronic Conditions Over the Life Span and Their Age of Onset

The National Institutes of Health (NIH) is preparing to publish a Notice of Funding Opportunity (NOFO) for randomized controlled clinical trials focused on the long-term effects of nutritional interventions on age-related chronic conditions. The objective is to gain a deeper understanding of how various nutritional factors influence health across the lifespan, necessitating trials with a minimum duration of five years to adequately assess outcomes. This initiative is crucial for developing effective dietary practices that can mitigate health risks associated with aging. Interested applicants, including Indian/Native American Tribal Governments, federal agencies, and community organizations, are encouraged to start forming collaborations, as applications will be accepted starting June 25, 2026, with an estimated award date of July 25, 2027. For further inquiries, potential applicants can reach out via email to the NIA Scientific Contact at NIA-NOFO-Scientific@nih.gov.