The Metastasis Research Network (MetNet): MetNet Research Projects (U01 Clinical Trial Not Allowed)
Grant Opportunity Analysis
The National Institutes of Health (NIH) is offering a funding opportunity titled "The Metastasis Research Network (MetNet): MetNet Research Projects (U01 Clinical Trial Not Allowed)" through a cooperative agreement. This initiative invites applications for research projects that utilize systems-level approaches to address critical gaps in metastasis research, aiming to enhance understanding of metastasis as a complex, whole-body issue while integrating with the existing MetNet framework. The focus areas include dormancy, early dissemination, microenvironment interactions, and therapeutic responses in various cancers, with a budget limit of $500,000 in direct costs annually for up to five years. Interested applicants, including foreign organizations, must adhere to specific eligibility criteria and submit their applications by the deadlines of June 5, 2026, October 5, 2026, and June 5, 2027, with the earliest project start date anticipated for April 2027. For further inquiries, applicants can contact the NCI MetNet Program at NCIMetNet@mail.nih.gov.
Eligible Applicants
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.NIH will no longer issue awards (i.e., new, renewal, or non-competing continuation) to domestic or foreign entities that involve foreign subawards/subcontracts. All NIH-funded research involving foreign subawards/subcontracts must be submitted in response to a NOFO that is specifically designated for funded international collaborations. This new requirement was effective, May 1, 2025.Applications involving foreign subawards/subcontracts submitted in response to this NOFO will be deemed noncompliant and will not be considered for funding. This policy applies to all monetary international collaborations resulting in foreign subawards/subcontracts, however, it does not preclude unfunded international collaborations or foreign components, funding for foreign consultants, or procurement of unique equipment or supplies from foreign vendors.