The National Institutes of Health (NIH) is preparing to publish a Notice of Funding Opportunity (NOFO) titled "NINR Areas of Emphasis for Research to Optimize Health for All (R01 Clinical Trial Optional)." This initiative aims to support research projects that enhance health outcomes across diverse populations, encouraging collaborations and innovative approaches in nursing research. The funding opportunity will utilize the R01 activity code, with no cost-sharing or matching requirements, and is categorized under health-related discretionary funding. Interested applicants should note that the synopsis is expected to be posted on January 8, 2025, with a closing date for applications on February 5, 2025, and an estimated award date of December 1, 2025. For further details, potential applicants are encouraged to prepare their proposals in advance of these key dates.